方法：收集急性闭角型青光眼患者25例，对初诊、治疗第1、2、3d的眼压与角膜结膜特征对比分析。

结果：急性闭角型青光眼发作时角膜上皮厚度、全层厚度分别为72.76±11.95、589.40±66.91μm； 结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为58.88±12.87、299.76±94.86、358.64±102.55μm； 治疗第1d角膜上皮厚度、全层厚度分别为69.28±12.65、579.04±67.88μm； 结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为57.04±12.05、282.44±91.47、339.48±100.28μm； 治疗第2d角膜上皮厚度、全层厚度分别为66.76±11.42、563.32±63.87μm； 结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为54.76±11.01、267.00±98.54、322.16±106.12μm； 治疗第3d角膜上皮厚度、全层厚度分别为65.16±12.25、550.36±71.48μm； 结膜上皮层厚度、结膜固有层厚度和结膜全层厚度为53.36±10.29、252.76±99.32、306.52±107.31μm； 治疗前、治疗第1、2、3d时4个测量时间点的眼压、角膜上皮厚度、角膜全层厚度、结膜上皮厚度、结膜固有层厚度和结膜全层厚度差异都有统计学意义(P<0.05)。

结论：青光眼急性发作时角膜结膜水肿厚度增加，并随眼压的降低而变薄。

METHODS:Twenty-five patients with AACG were recruited. Intraocular pressure(IOP)and morphological characteristic of cornea and conjunctiva were measured at their first visit, 1, 2 and 3d after they began the treatments.

RESULTS:The corneal epithelium thickness and corneal thickness of patients with acute attack of angle closure glaucoma were 72.76±11.95μm and 589.40±66.91μm; the conjunctival epithelial layer thickness was 58.88±12.87μm; the thickness of conjunctive stroma was 299.76±94.86μm; the conjunctival full thickness was 358.64±102.55μm. The corneal epithelium thickness and corneal thickness at the first day of the treatment were 69.28±12.65μm and 579.04±67.88μm; the conjunctival epithelial layer thickness was 57.04±12.05μm; the thickness of conjunctive stroma was 282.44±91.47μm; the conjunctival full thickness was 339.48±100.28μm. the corneal epithelium thickness and corneal thickness at the second day of treatment were 66.76±11.42μm and 563.32±63.87μm; the conjunctival epithelial layer thickness was 54.76±11.01μm; the thickness of conjunctive stroma was 267.00±98.54μm; the conjunctival full thickness was 322.16±106.12μm. the corneal epithelium thickness and corneal thickness of the third day treatment are 65.16±12.25μm and 550.36±71.48μm; the conjunctival epithelial layer thickness was measured 53.36±10.29μm; the thickness of conjunctive stroma was 252.76±99.32μm; the conjunctival full thickness was 306.52±107.31μm. The difference of IOP, corneal epithelial thickness, corneal thickness, conjunctival epithelial layer thickness, conjunctival stroma thickness and conjunvtival full thickness had statistically significant(P<0.05).

CONCLUSION:The corneal and conjunctival thickness in patients at acute attack of angle closure glaucom increase. The edema level decreases with IOP.