方法：回顾性分析2014-09/2015-03在我院行微创玻璃体切割联合微切口白内障超声乳化并Ⅰ期植入IOL手术者共48例54眼。术前、术后5d，1、3mo记录最佳矫正视力(best corrected visual acuity，BCVA)、眼压、角膜散光、角膜内皮细胞计数，观察眼底情况、IOL位置以及术后低眼压、角膜水肿、后发性白内障、高眼压等并发症。

结果：所有患者手术均顺利完成。术后3mo BCVA较术前提高49眼(91%)，视力无改善5眼(9%)，无视力较术前下降者。手术前后眼压、角膜内皮细胞计数差异有显著统计学差异(P<0.01)，术后3mo角膜内皮细胞丢失率为11.71%±8.12%。角膜散光术后早期增加(P<0.05)，术后3mo与术前无统计学差异(P>0.05)。术后发生一过性高眼压(术后1mo内眼压>25mmHg)者6眼，早期角膜水肿发生7眼，前房有成形渗出2眼，发生后囊膜混浊3眼，其中2眼行YAG激光后囊截开术，视力明显提高。术后眼底视网膜均平伏，无发生视网膜脱离、脉络膜脱离、感染性眼内炎、新生血管性青光眼、低眼压患者，无并发IOL偏位、脱位病例。

结论：微创玻璃体切割联合微切口白内障超声乳化并Ⅰ期植入IOL手术适应证广泛、损伤小、恢复快、并发症少，是一种安全有效的手术方式，值得推广和应用。

METHODS: A retrospective analysis were done in 48 patients with 54 eyes from September 2014 to March 2015 in our hospital who received micro-incision vitrectomy combined with micro-incision phacoemulsification and immediate IOL implantation. Best corrected visual acuity(BCVA), intraocular pressure(IOP), corneal astigmatism and corneal endothelial cells were recorded before and at 1d, 1 and 3mo after operations. All patients were followed up to observe the fundus, IOL position and postoperative low IOP, corneal edema, posterior capsular opacification, ocular hypertension and other complications.

RESULTS: All procedures were successfully completed. After 3mo, BCVA increased in 49 eyes(91%)compared to that preoperative. Visual acuity did not improve in 5 eye(9%), and no visual acuity decreased. The differences on IOP and corneal endothelial cells before and after operation were significant(P<0.01). The percentage of lost corneal endothelial cells was 11.71±8.12% at 3mo. At early stage postoperatively corneal astigmatism increased(P<0.05)and there was no difference between that pre-operative and 3mo post-operatively(P>0.05).There were 6 eyes with transient high IOP(IOP greater than 25mmhg in 1mo), 7 eyes with corneal edema at early stage, 2 eyes with formed exudation in anterior chamber, and there were 3 eyes with posterior capsular opacification, in which 2 eyes were performed with YAG laser for posterior capsulotomy and whose visual acuity improved significantly. There was no retinal detachment, choroidal detachment, endophthalmitis, neovascular glaucoma, hypotony, IOL misalignment or dislocation.

CONCLUSION: Micro-incision vitrectomy combined with micro-incision phacoemulsification and immediate IOL implantation is a safe and effective method with wide application, small damage, rapid recovery and less complication, and it is worth of promotion.