方法：前瞻性分析2012-07/2014-07随访资料完整的16例30眼近视及近视散光的连续性病例，术中使用治疗性准分子激光角膜切削术去除角膜上皮，再进行屈光性准分子激光角膜切削完成屈光矫治。随访记录术后1、3、6、12mo的视裸眼视力(UCVA)、角膜haze及残余等效球镜度(MRSE)。

结果：术后各时期UCVA≥0.5者与术前BCVA差异无统计学意义(P>0.05)。术后各时期UCVA≥1.0者较术前BCVA差异经卡方检验两两比较差异亦无统计学意义(P>0.006)。术后不同时期角膜haze值差异有统计学意义(F=16.751，P=0.000)。术后1mo角膜haze值为0.71±0.25，随时间推移角膜haze逐渐减轻，无2级以上haze出现。术后1mo MRSE为0.9±0.87D，较术后3mo(0.5±0.65D)差异有统计学意义(t=2.017，P=0.048)，而MRSE在术后3、6mo(0.5±0.65、0.5±0.45D)及12mo(0.25±0.4D)差异无统计学意义(F=2.389，P=0.098)。

结论：本组研究获得较好的临床视力结果，术后1mo有轻度远视漂移及较明显的角膜haze，对于其远期屈光稳定性及视觉质量等仍需大样本及分组的临床研究。

METHODS:A prospective analysis for 16 consecutive patients(30 eyes)with myopia and myopic astigmatism from July 2012 to July 2014 in our hospital underwent transepithelial photorefractive keratectomy(T-PRK, PRK with epithelial removal by PTK). Uncorrected distant visual acuity(UCVA), haze formation and remaining manifest refractive spherical equivalent(MRSE)were recorded before and at 1,3,6 and 12mo after operations.

RESULTS:There were no significant differences(P>0.05)in patients had an postoperative UCVA≥0.5 at 1, 3, 6 and 12mo compared with preoperative best corrected visual acuity(BCVA), and the same as the patients had an UCVA≥1.0(P>0.006). There were significant differences in haze values between different postoperative times(F=16.751, P=0.000). The haze value at 1mo was 0.71±0.25, which was gradually reduced with the time, and no more than 2 grades. Postoperative MRSE at 1mo was 0.9±0.87D, compared with 0.5±0.65D at 3mo, the difference was statistically significant(t=2.017, P=0.048). While the difference was not statistically significant(F=2.389, P=0.098)among MRSE at 3, 6(0.5±0.45D)and 12mo(0.25±0.4D).

CONCLUSION:The study obtained good clinical visual acuity. It shows slightly hyperopic shift and corneal haze at 1mo postoperatively. Large sample and grouped clinical research should be taken for the long-term stability of refraction and visual quality.