方法：同一天于我院眼表疾病专科就诊并诊断为干眼的患者16例，利用非侵入性眼表综合分析仪Keratograph 5M对患者进行泪膜破裂时间(BUT)、泪河高度测定以及行睑板腺检查。根据结果进行个体化治疗，并于治疗2wk后复查。将患者治疗前后的BUT、泪河高度、睑板腺缺失面积评分进行统计分析。

结果：干眼患者16例中，治疗前的泪河高度、BUT、睑板腺缺失面积评分分别为0.276±0.073mm、6.343±3.304s、3.78±1.36分，治疗2wk后分别为0.292±0.065mm、8.876±3.670s、2.25±1.16分，其中BUT及睑板腺评分在治疗前后的差异均有统计学意义。

结论：非侵入性眼表综合分析仪在指导干眼患者个体化治疗中具有方便、快捷、无创的特点，同时可以客观地评价治疗效果。

METHODS:Sixteen patients who were diagnosed with dry eye in the same day were included. Tear film break-up time(BUT), lacrimal river height, and the meibomian glands were measured with a latest Keratography 5M. The patients received individualized treatment according to the examination and then recheck the items mentioned above 2wk post-treatment. The items were used for statistical analysis.

RESULTS:The scores of all subjects were 0.276±0.073mm for lacrimal river height, 6.343±3.304s for BUT, 3.78±1.36scores for deficiency area of meibomian glands in the first check-up and 0.292±0.065mm,8.876±3.670s,2.25±1.16scores respectively at 2wk post-treatment. The BUT and deficiency area of meibomian glands were both statistically significantly.

CONCLUSION:The noninvasive Keratography 5M is a conveinent and atraumatic tool in the diagnosis and treatment for dry eye. It can evaluate the treatment effectiveness objectively and systematically.