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[摘要]
目的:比较光学相干生物测量仪(Lenstar)、三维眼前节分析仪(Pentacam)和A型超声测量仪(A-scan)在白内障患者中测量角膜中央厚度、角膜曲率、前房深度和眼轴长度结果的差异。
方法:分别用3种仪器对158例(158眼)白内障患者进行眼部生物测量,比较角膜中央厚度、角膜曲率、前房深度和眼轴长度的结果,采用重复测量的方差分析及Pearson相关分析,一致性比较采用Bland-Altman统计分析法。
结果:Lenstar 和 Pentacam测得的角膜中央厚度分别为536.54±27.90μm和541.46±29.85μm,两者差异有统计学意义(t=-5.439; P<0.001); K值分别为43.87±1.45D和43.86±1.44 D,两者差异无明显统计学意义(t=-0.348, P>0.05)。Pentacam、Lenstar和 A超测量的前房深度分别是2.73±0.38mm、2.71±0.38mm和2.85±0.40mm,三者差异均有统计学意义(F=309.94, P<0.001),Pearson 相关分析显示三者呈正相关(r=0.989, 0.978, and 0.977; P<0.001),但变异系数较小(CV=3.12%)。A超和Lenstar测量的眼轴长度分别是24.28±1.70mm和24.52±1.73mm,两者差异有统计学意义(t=-19.482, P<0.001, r=0.996; P<0.001)。Bland-Altman分析显示,对于这几种眼前节参数,三种方法测量的一致性较好。
结论:三种仪器测量的结果尽管有一定差异,但Lenstar 和Pentacam的生物测量可重复性好,操作简便更易用于白内障患者的检查。
[Key word]
[Abstract]
AIM: To compare the central corneal thickness(CCT), keratometry(K)reading, anterior chamber depth(ACD), and axial length(AL)measured with Lenstar and Pentacam with those obtained with the ultrasound(US)pachymetry in the cataract patients.
METHODS: A total of 158 eyes of 158 patients were examined in this study. The CCT, average K, ACD and AL obtained by Lenstar and/or Pentacam were compared with those obtained from US pachymetry using repeated-measures analysis of variance, Pearson correlation coefficients and Bland-Altman analyses.
RESULTS: The mean CCT obtained using Lenstar and Pentacam were 536.54±27.90μm and 541.46±29.85μm(t=-5.439; P<0.001). The mean Km obtained using Lenstar and Pentacam methods were 43.87±1.45D and 43.86±1.44 D(t=-0.348, P>0.05). The mean ACD measured using the Pentacam, Lenstar, and US pachymetry were 2.73±0.38mm, 2.71±0.38mm, and 2.85±0.40 mm, respectively(F=309.94, P<0.001), and they were positively correlated(r=0.989, 0.978, and 0.977; P<0.001)and the coefficient of variation was small(3.12%). The mean AL obtained by US pachymetry and Lenstar were 24.28±1.70mm and 24.52±1.73 mm, respectively(t=-19.482, P<0.001, r=0.996; P<0.001). The Bland-Altman analysis showed that the three methods were comparable for CCT, Km, ACD and AL.
CONCLUSION: Although there were statistically significant differences, the measurements obtained by the Lenstar and the Pentacam were highly repeatable and the instruments easy to use.
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