方法：选取行小梁切除术后1～4wk来院复诊的青光眼患者26例30眼，对功能不良的滤过泡进行针刺分离联合膜下注射5-氟尿嘧啶进行治疗。观察滤过泡形态、眼压和并发症，随访3mo。

结果：针刺分离后滤过泡形态有24眼表现为功能性滤过泡。针刺分离前患者眼压为26.4±2.8mmHg，分离后眼压为14.1±1.1mmHg，两者差异有统计学意义(P<0.05)。治疗后治愈率70%(21眼)，有效率17%(5眼)，总有效率87%。常见并发症包括结膜下出血、角膜上皮点状剥脱和前房积血。

结论：针刺分离联合结膜下注射5-氟尿嘧啶对小梁切除术后功能不良滤过泡有着良好效果，值得在临床治疗中推广应用。

METHODS:Needle revision combined with subconjunctival injection of 5-FU treatment was conducted on 30 eyes in 26 patients with disfunctional blebs at clinic visits at 1～4wk immediately after trabeculectomy. The morphology, intraocular pressure(IOP)and complications of the filtering blebs were observed, and all the patients were followed up for 3mo.

RESULTS:The morphology of filtering blebs was normal in 24 eyes after needle revision treatment. The pre-treatment IOP was 26.4±2.8mmHg, and the post-treatment IOP was 14.1±1.1mmHg, and the difference was statistically significant(P<0.05). The cure rate was 70%(21 eyes), effective rate was 17%(5 eyes), and the total was 87%. Common complications included subconjunctival hemorrhage, corneal epithelium dot stripped and hyphema.

CONCLUSION:The combination of needle revision and 5-FU has a good effect for failed filtering blebs after trabeculectomy. It is worthy promotion in clinical treatment.