目的：为了提高眼科学教学效率和教学质量，培养学生分析和解决临床实际问题的能力，将以案例为基础(case based-learning，CBL)和以问题为基础(problem-based learning，PBL)相结合教学模式引入眼科学临床教学中，并评价其教学效果。

方法：对昆明医科大学2013级本科临床医学专业两个班级的131名学生分别采用CBL与PBL相结合教学模式和传统课堂教学模式进行急性闭角型青光眼章节的教学。通过课堂测验、临床技能操作考核等综合评价两种教学方法的教学效果。

结果：CBL与PBL相结合教学模式班级综合成绩明显优于传统课堂教学方式班级。

结论：应用CBL与PBL相结合教学模式能够提高学生学习兴趣，促进学生自主学习，有助于提高学生思考问题、分析和解决问题的能力。

AIM: To improve the efficiency and quality of teaching, and to cultivate students' ability to analyze and solve clinical problems, the case-based learning(CBL)combined with problem-based learning(PBL)teaching mode is introduced into the clinical teaching of ophthalmology.

METHODS:Two classes(total 131 students)of 2013 grade major in clinical medicine, Kunming Medical University, were randomly selected as experimental group using CBL combined with PBL teaching mode, and control group using traditional teaching mode. The part of acute angle-closure glaucoma was taught. The scores of the experimental group were compared with that of control group at the end of term.

RESULTS: The mean scores of CBL combined with PBL teaching group were significantly higher than that of traditional teaching group.

CONCLUSION: The application of CBL combined with PBL in the clinical teaching of ophthalmology has obvious advantages in improving the learning interests and promoting students' self-learning ability. It is helpful in improving the students' ability of independent-thinking, analyzing and solving problem.

国家自然科学基金资助项目(No.81460085)