方法：收集2014-01/11难治性青光眼患者24例30眼，施行Ex-press微型引流器(P-50)植入联合深层巩膜切除术。术后随访12mo，分析术前及术后疼痛感、眼压、视力、并发症等情况。

结果：术后随访期间所有患者眼痛症状均缓解。术前平均眼压为51.15±2.60mmHg，末次随访时平均眼压15.11±2.51mmHg，术后眼压与术前相比，差异有统计学意义(P<0.05)。术后视力有提高者8眼，无显著改变者22眼。术后前房出血2眼(7%)，1wk后出血吸收。

结论：Ex-press微型引流器植入联合深层巩膜切除术是治疗难治性青光眼相对安全、有效的方法，能显著降低眼压，减少患者痛苦，且并发症少。

METHODS: Thirty eyes in 24 patients with refractory glaucoma were treated by Ex-Press miniature(P50)implantation with deep sclerectomy. The patients' symptom, intraocular pressure(IOP), visual acuity and complications were analyzed in a 12mo follow-up period.

RESULTS: During the follow-up period, all patients' ocular pain was reduced. The mean IOP before operation and at the last follow-up time were 51.15±2.60mmHg(1kPa=7.5mmHg)and 15.11±2.51mmHg, respectively, there was significant difference(P<0.05). Postoperative visual acuity was improved in 8 eyes,had no significant change in 22 eyes. After operation, hyphema of anterior chamber appeared in 2 eye(7%), which were obsorbed after 1wk.

CONCLUSION: Ex-Press miniature implantation combined with deep sclerectomy surgery is a relatively effective and safe treatment for the patients with refractory glaucoma. This method can significantly degrade the IOP, lessen ocular pain and reduce the complications risk.