方法：前瞻性研究。渗出型老年黄斑变性患者112例112眼，随机分为研究组和对照组，各56例56眼，研究组患者采用玻璃体腔内注射康柏西普治疗，对照组采用保守治疗，观察治疗前后两组患者裸眼视力及黄斑中心凹视网膜厚度。

结果：研究组患者治疗后视力明显提高，且治疗后6mo提高最明显。研究组患者治疗后黄斑中心凹视网膜厚度均减低，且治疗后6mo减低最明显。

结论：玻璃体腔内注射康柏西普能有效提高渗出型老年黄斑变性患者视力，降低黄斑中心凹厚度。

METHODS:Prospective study. Totally 112 senile patients(112 eyes)with exudative macular degeneration were randomly divided into study group and the control group, 56 cases in each group. The study group were treated with intravitreal injection of conbercept. The control group received conservative treatment. Uncorrected visual acuity and foveal retinal thickness were observed before and after treatment in the two groups.

RESULTS: Visual acuity of study group improved significantly, and the most obvious improvement was observed at 6mo after treatment. Foveal retinal thickness of study group was reduced after treatment, and the most obvious decrease was observed at 6mo after treatment.

CONCLUSION: Intravitreal injection of conbercept can improve visual acuity reduced foveal thickness in senile patients with exudative age-related macular degeneration.