目的：通过OCT检查比较青少年屈光参差性弱视眼与非弱视眼视盘周围神经纤维层厚度、视盘地形图参数的差异，研究弱视眼视盘参数的特征。

方法：选取青少年屈光参差性弱视34例34眼，利用Cirrus频域光学相干断层扫描(optical coherence tomography，OCT)技术分别检测双眼视盘周围视网膜神经纤维层(retinal nerve fiber layer，RNFL)厚度及视盘地形图参数，比较同一受检者弱视眼与非弱视眼的差异。

结果：弱视眼视盘周围平均神经纤维层厚度、各区域神经纤维层厚度与健侧眼比较无明显统计学差异； 视盘地形图各参数中弱视眼的视盘面积较健侧眼增大，差异有统计学意义(t=2.8054，P=0.0263)，且弱视眼的视盘面积与视盘鼻侧RNFL厚度及盘沿面积呈正相关(r=0.7592、0.7501，P=0.0289、0.0321)。

结论：青少年屈光参差性弱视眼视盘参数与非弱视眼存在一定差异。

AIM: To compare the peripapillary retinal nerve fiber layer(RNFL)thickness and peripapillary topographic map's parameters between amblyopic eyes and non-amblyopic eyes in adolescent with anisometropic amblyopia by optical coherence tomography(OCT).

METHODS: Thirty-four juveniles with anisometropic amblyopia were selected. Peripapillary RNFL thickness and peripapillary topographic map were measured by frequency domain OCT with both eyes in all participants, and the differences between amblyopic eyes and non-amblyopic eyes were compared.

RESULTS: There was no significant difference in average thickness of peripapillary RNFL and in any other region of peripapillary RNFL. The disc area in amblyopic eyes was bigger than that in non-amblyopic eyes(t=2.8054,P=0.0263). The disc area in amblyopic eyes were significantly related to the thickness of nasal RNFL and the rim area(r=0.7592,0.7501; P=0.0289,0.0321).

CONCLUSION: There existed some difference in peripapillary structure between amblyopic eyes and non-amblyopic eyes in adolescent with anisometropic amblyopia.