[关键词]
[摘要]
目的：比较自体结膜瓣移植术(conjunctival autograft transplant， CAT)和角膜缘干细胞移植术(limbal conjunctival autograft transplant， LCAT)治疗原发性翼状胬肉的临床效果。
方法：前瞻性、随机、对照病例研究。收集2014-01/2015-01在解放军第四七四医院诊断为原发性翼状胬肉患者共120例120眼，依次纳入本研究，奇数者行CAT，偶数者行LCAT。
结果：术后随访1a，完成随访107例107眼，CAT组患者54例54眼，术后复发4眼，复发率7.4%； LCAT组患者53例53眼，术后复发2眼，复发率3.8%。两组间复发率无统计学意义(P=0.678)。
结论：CAT组和LCAT组均能有效治疗原发性翼状胬肉，降低术后翼状胬肉复发率，但LCAT是治疗原发性翼状胬肉的最优术式。
[Key word]
[Abstract]
AIM: To compare the safety and efficacy of conjunctival autograft transplant(CAT)and limbal-conjunctival autograft transplant(LCAT)for primary pterygium.
METHODS: In this prospective, randomized and controlled clinical study, 120 patients(120 eyes)diagnosed with primary pterygium were collected in NO.474 Hospital of Chinese PLA from January 2014 to January 2015. The 120 patients enrolled in the study in turn, and divided into two group by the odd and even number. The odd number underwent CAT and the even number underwent LCAT.
RESULTS:One hundred and seven patients(107 eyes)completed the follow-up of 1a, including 54 patients(54 eyes)from the CAT group and 53 patients(53 eyes)from the LCAT group. Four patients(4 eyes, recurrence rate 7.4%)in the CAT group and 2 patients(2 eyes, recurrence rate 3.8%)in the LCAT group developed recurrence. However, there were no significant in recurrence rate between CAT group and LCAT group(P=0.678).
CONCLUSION:CAT and LCAT might be both effective treatment for primary pterygium for reducing the recurrence rate of pterygium. However, LCAT is the optimal surgical method for primary pterygium.
[中图分类号]
[基金项目]
新疆维吾尔自治区科技支疆项目(No.201491171)
