目的：评价两种角膜绷带镜Senofilcon A和Balafilcon A在准分子激光上皮下角膜磨镶术(laser-assisted subepithelial keratomileusis， LASEK)术后应用的临床安全性和有效性。

方法：行LASEK患者38例76眼，术后38眼配戴senofilcon A角膜绷带镜，38眼配戴Balafilcon A，连续配戴7d。术后第3、7d由患者对两眼主观症状(眼痛、异物感、流泪)进行评分。7d摘镜后检查视力和角膜染色情况。

结果：配戴两种镜片术后主观症状中眼痛感和流泪两眼存在差异，Senofilcon A眼症状更轻，眼痛感在术后3、7d两组比较差异有统计学意义(Z=-4.146，P=0.000； Z=-2.814，P=0.005)。流泪在术后3、7d时两组比较差异有统计学意义为(Z=-2.309，P=0.021； Z=-3.276，P=0.001)。而干涩感在术后3、7d时两组比较无统计学差异(Z=-0.447，P=0.655； Z=-0.966，P=0.334)。术后7d摘除镜片后，Senofilcon A眼视力优于Balafilcon A眼，差异有统计学意义(t=3.800，P=0.001)。两组摘镜后，角膜染色大多为1～2个象限的少量点染，对比有统计学差异(Z=-2.384，P=0.017)。

结论：Senofilcon A以及Balafilcon A角膜绷带镜在LASEK术后应用是安全有效的，Senofilcon A对角膜上皮瓣的恢复更优些。

AIM: To investigate the clinical safety and effectiveness of the two kind of bandage contact lenses: Senofilcon A(Johnson & Johnson Acuvue Oasys)and Balafilcon A(Bausch& Lomb pure vision)after laser-assisted subepithelial keratectomy(LASEK).

METHODS: Thirty-eight patients(76 eyes)who had undergone the LASEK were divided into two groups. One group of patients wore Balafilcon A, the other group of patients fitted with Senofilcon A. The lenses were worn continuously for 7d. This was a seven-day experience and the patients scored for the symptom of the eyes(sore eyes, foreign body sensation and tearing)on the third day and the seventh day. Both of the two groups of patients taken off the soft contact lens on the seventh day and let their vision and corneal staining checked.

RESULTS: The symptoms of eye sore and tearing of the two groups patients were different. The patients who wore the Senofilcon A were better. The pain of eyes were also different at 3 and 7d after surgeries(Z=-4.146, P=0.000; Z=-2.814, P=0.005). The difference on tearing between the two groups at 3 and 7d after surgeries were significant(Z=-2.309, P=0.021; Z=-3.276, P=0.001). There was no difference on sensation of dryness between the two groups at 3 and 7d after surgeries(Z=-0.447, P=0.655; Z=-0.966, P=0.334). After the lenses were taken off, the visual acuity of patients wearing Senofilcon A was better(t=3.800, P=0.001); corneal staining showed limited spots in 1-2 quadrants with significant difference(Z=-2.384,P=0.017).

CONCLUSION: The Senofilcon A(Johnson & Johnson Acuvue Oasys)and Balafilcon A(Bausch& Lomb pure vision)bandage contact lenses are safe and effective after LASEK, and the former is better than the latter in epithelial regeneration.