[关键词]
[摘要]
IgG4相关性眼病是一种与IgG4密切相关的慢性系统性疾病，是以血清IgG4水平升高及IgG4阳性浆细胞浸润泪腺、眼外肌、眶下神经等眼部附属器为特征，而且经常是全身系统性病变的首发症状。糖皮质激素对该病治疗有效。本文就近年来IgG4相关性眼病的病因发病机制，临床表现，诊断及治疗方面的最新进展进行综述。
[Key word]
[Abstract]
IgG4-related ocular disease, a chronic systemic disease with lgG4, is characterized by elevated serum levels of lgG4 and a dense lymphoplasmacytic infiltrate rich in lgG4-positive plasma cells in involved ocular adnexa such as lacrimal glands, extraocular muscles, infraorbital nerve and so on. It is often the first symptom of systematic disease. IgG4-related ocular disease has a good response to steroids. In this article we will review relevant literatures of this disorder.
[中图分类号]
[基金项目]
黑龙江省自然科学基金项目(No.D200949); 黑龙江省教育厅科学技术研究项目(No. 11541219); 黑龙江省卫生厅科研项目(No.2007-222); 哈尔滨市科技局资助项目(No.2007RFQXS090)
