方法：选取行白内障超声乳化术的2型糖尿病维吾尔族白内障患者30例40眼作为试验组，同时选取行白内障超声乳化术的无糖尿病维吾尔族患者38例45眼作为对照组。分别于术前、术后1、7、30、90、180d，观察患者干眼症状、角膜上皮荧光染色(FL)、泪膜破裂时间(BUT)及基础泪液分泌试验(SⅠt)，并对数据进行统计学分析。

结果：两组干眼症状评分的比较，其结果表明试验组和对照组比较差异有统计学意义(P<0.05)，不同时间点比较差异有统计学意义(P<0.05)。对照组术后180d与术前干眼症状评分，差异无统计学意义。两组FL、BUT 和SⅠt在不同的组比较差别有统计学意义(P<0.05)，不同时间点比较差别有统计学意义(P<0.05)。超声乳化术后1、7、30d，两组与术前相比较，FL增加、BUT缩短、SⅠt分泌减少，差异有统计学意义(P<0.05)。术后90d，两组与术前相比较，试验组FL增加、BUT缩短、SⅠt分泌减少，差异有统计学意义(P<0.05)； 对照组FL、BUT、SⅠt分泌接近术前水平，差异无统计学意义。术后180d，两组与术前相比较，FL、BUT、SⅠt接近术前水平，差异无统计学意义。

结论：合并2型糖尿病的维吾尔族白内障患者泪膜功能较差，易患干眼。在行白内障超声乳化术后短期泪膜稳定性有较大影响，后期有逐步恢复趋势，但较其它地区恢复时间较长，可能与新疆地区风沙大等多种因素有关，是否与种族有一定的相关性，还需要进一步研究。临床上应该积极采取各种预防及治疗措施。

METHODS: Thirty cataract patients in Xinjiang Uygur Autonomous Region with type 2 diabetes mellitus(40 eyes)who underwent phacoemulsification procedure were included in the study as experimental group. And 38 cataract patients in Xinjiang Uygur Autonomous Region without diabetes mellitus(45 eyes)operated in the same period were included in this study as contrast group. The Symptoms of dry eyes, corneal fluorescein(FL)staining, break-up time(BUT)of tear film, and Schirmer Ⅰ test(SⅠt)value were analyzed and compared between two groups preoperatively and 1d, 7d, 30d, 90d, 180d postoperatively.

RESULTS: Compared two groups of dry eye symptom, the results showed the difference was statistically significant. Different time between both groups, the difference was statistically significant. Compared preoperative and postoperative 180d in control group with dry eye symptoms, the difference was statistically significant. Two groups of FL, BUT and SⅠt in a different set of comparison, the difference was statistically significant. Different time between both groups, the difference was statistically significant. Postoperative 1d, 7d and 30d compared with the preoperative, FL increased, BUT shorted, SⅠt secretion decreased in two groups, the difference was statistically significant. Postoperative 90d compared with the preoperative, experimental group increased, FL increased, BUT shorted, SⅠt reduced in two groups, the difference was statistically significant. The control secretion with FL, BUT, SⅠt were closed to preoperative levels, the differences were no statistically significant. Postoperative 180d compared with the preoperative, FL, BUT, SⅠt were closed to preoperative levels in two groups, the differences were no statistically significant.

CONCLUSION: Type 2 diabetic cataract patients in Xinjiang Uygur Autonomous Region have tear film dysfunction and are susceptible to dry eye. The tear film stability of diabetic cataract reduces significantly at early stage after phacoemulsification and recover much slowly. The secretion and stability of tear decreased in the short term after phacoemulsification procedure, and would recover gradually. The reason may be related to many factors such as the sandstorm in Xinjiang Uygur Autonomous Region. More research is needed. The preventions and treatment should be taken clinically.