方法：选取140例140眼白内障超声乳化联合IOL植入术后干眼患者，随机分为对照组和观察组，分别使用聚乙二醇滴眼液和聚乙二醇滴眼液联合重组牛bFGF眼用凝胶治疗。在治疗前和治疗后1mo进行干眼症状评分和基础泪液分泌试验Ⅰ(Schirmer Ⅰ test，SⅠt)、泪膜破裂时间(tear break-up time，BUT)、角膜荧光素染色检测，统计分析两组疗效差异。

结果：治疗前两组患者干眼症状评分和SⅠt、BUT均无统计学差异(P>0.05)。治疗后经配对t检验发现以上三个测量值在两组内比较，差异有统计学意义(P<0.05)，均有明显改善。但治疗后组间比较仅发现观察组的干眼症状评分和BUT明显优于对照组，差异有统计学意义(P<0.05)，观察组的角膜荧光素染色评分下降率显著高于对照组，差异有统计学意义(P<0.05)。

结论：针对白内障超声乳化联合IOL植入术后干眼的治疗，联合应用传统人工泪液聚乙二醇和重组牛bFGF较单独应用聚乙二醇可显著改善患者眼部不适，明显延长BUT，有效降低角膜荧光素染色评分，疗效更为理想。

METHODS: One hundred and forty patients were selected with one dry eye after the surgery above, and randomly divided into control group and observation group. The two groups were treated with polyethylene glycol eye drops and polyethylene glycol eye drops combined with recombinant bovine basic fibroblast growth factor eye gel respectively. We tested their dry eye symptom score, Schirmer Ⅰ test(SⅠt); tear break-up time(BUT)and corneal fluorescein staining before and 1mo after treatment. Finally, statistical analysis of the two groups of efficacy differences were carried out.

RESULTS: Before treatment, there was no significant difference in dry eye symptom score, SⅠt and BUT between two groups(P>0.05). After treatment, the three measured values above were significantly improved within each group by Paired t-test(P<0.05), while only the dry eye symptom score and BUT in observation group were significantly better than the control group(P<0.05). The decrease rate of corneal fluorescein staining score in the observation group was significantly higher than that in control group(P<0.05).

CONCLUSION: For the treatment of dry eye after cataract phacoemulsification combined with intraocular lens implantation, combined application of the traditional artificial tears polyethylene glycol and recombinant bovine basic fibroblast growth factor is more effective than those only using polyethylene glycol. Combined treatment can improve the eye discomfort, prolong the time of BUT, and reduce the corneal fluorescein staining score more significantly. The medicine has certain application value in clinical.