方法：根据眼底检查及眼底造影结果将所有患者分为两组：无糖尿病视网膜病变组(no diabetic retinopathy，NDR)，非增殖型糖尿病视网膜病变组(non-proliferative diabetic retinopathy，NPDR)，运用彩色多普勒超声(color Doppler flow imaging，CDFI)测量供应眼部循环的眼动脉(ophthalmic artery，OA)以及供应脉络膜循环的睫状后动脉(posterior ciliary artery，PCA)的收缩峰值流速(peak systolic velocity，PSV)，舒张末流速(end diastolic velocity，EDV)以及阻力指数(resistance index，RI)，重点观察服药前以及服用芪明颗粒3mo之后的OA和PCA的血流参数，定量评价芪明颗粒对糖尿病患者眼部血流动力学的影响。

结果：在服用芪明颗粒3mo后无糖尿病视网膜病变和非增殖型糖尿病视网膜病变的两组患者眼动脉和睫状后动脉的PSV及EDV均有所加快，阻力指数下降，且与服药之前相比具有显著差异。

结论：芪明颗粒可以改善眼部微循环状态，包括视网膜及脉络膜，改善糖尿病患者眼部血液供应。

METHODS:According to the results of fundus fluorescein angiography(FFA), 45 diabetes patients were divided into no diabetic retinopathy(NDR)and non-proliferative diabetic retinopathy(NPDR)group. All the subjects were examined by color Doppler flow imaging(CDFI). We quantitated peak systolic velocity(PSV), end diastolic velocity(EDV)and resistance index(RI)of the ophthalmic artery(OA)and the posterior ciliary artery(PCA). After 3mo ingestion of Qi Ming Granule, all the subjects were examined by the same methods. The alterations of the hemodynamic parameters were observed before and after taking Qi Ming Granule.

RESULTS: After 3mo ingestion of Qi Ming Granule, there were significant increased in PSV and EDV of OA and PCA in the two groups, and RI were significantly decreased.

CONCLUSION: Qi Ming granule can accelerate the blood flow of retina and choroid, improve the ocular blood circulation of the patients with diabetes, and delay the occurrence and development of diabetic retinopathy.