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[摘要]
目的:观察在自体结膜移植术中使用医用生物蛋白胶再加配戴绷带式角膜接触镜治疗单纯翼状胬肉的疗效。
方法:收集单纯翼状胬肉患者37例52眼,随机分为观察组19例28眼和对照组18例24眼,观察组采用翼状胬肉切除加自体结膜移植联合医用生物蛋白胶再配戴绷带式角膜接触镜治疗; 对照组采用翼状胬肉切除联合自体结膜移植术治疗。观察比较两组患者的疗效。
结果:观察组患者手术时间19.34±2.31min、术后1、7d的异物感发生率为36%、11%,明显小于对照组患者(28.15±4.27min,79%,46%),而术后1d的完全愈合率(89%)明显高于对照组患者(46%), 差异均具有统计学意义(P<0.05); 两组患者术后6mo的复发率无明显统计学差异(P>0.05)。
结论:在胬肉切除加自体结膜移植手术中联合使用医用生物蛋白胶加配戴绷带式角膜接触镜能够明显缩短手术时间,消除患者异物感,提高患者术后创面的愈合速度。
[Key word]
[Abstract]
AIM: To research the treatment of pterygium by conjunctival autograft transplantation combined with biological fibrin glue and usage of bandage type latent lens.
METHODS: Thirty-seven cases of patients(52 eyes)with simple pterygium were collected. They were randomly divided into observation group with 19 cases(28 eyes)and the control group with 18 cases(24 eyes). The observation group were treated by conjunctival autograft transplantation combined with biological fibrin glue and usage of bandage type latent lens. The control group were treated by pterygium excision combined with conjunctival autograft transplantation. The curative effect of two groups of patients were observed and compared.
RESULTS: The operation time(19.34±2.31min)and the incidence rate(36%, 11%)of foreign body sensation at postoperative 1d, 7d of observation group were significantly lower than those(28.15±4.27min, 79%, 46%)in the control group. The total healing rate of postoperative 3d(89%)was significantly higher than that of the control group(46%), the difference was statistically significant(P<0.05). The recurrence rate was no significant difference between two groups at 6mo postoperative.(P>0.05).
CONCLUSION: Conjunctival autograft transplantation combined with biological fibrin glue and usage of bandage type latent lens can significantly decrease the operation time, eliminate the sense of foreign body in patients and improve the healing rate of the wound after operation. It is suitable for further promotion in the primary hospital.
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