方法：选取近视治疗中心就诊患者74例148眼，每位患者均使用A型超声角膜厚度测量计、眼前节光学相干断层扫描仪和Allergro Oculyzer角膜地形图三种仪器测量其中央角膜厚度。数据统计方式为组间两两比较使用配对t检验，组间的相关性使用Pearson相关性检验，组间测量方法的一致性采用Bland-altman方法。

结果：A型超声角膜测厚、Allergro Oculyzer角膜地形图测厚、OCT角膜测厚的平均值分别为532.17±22.94、526.53±24.52、532.62±23.59μm。三种方式组间配对t检验。A型超声角膜测厚组与Allergro Oculyzer角膜地形图测厚组比较差异有统计学意义(P<0.05)。A型超声角膜测厚组与OCT角膜测厚组比较差异无统计学意义(P>0.05)。Allergro Oculyzer角膜地形图测厚组与OCT角膜测厚组比较差异有统计学意义(P<0.05)。线性相关性统计分析显示A型超声角膜测厚组、Allergro Oculyzer角膜地形图测厚组、OCT角膜测厚组两两呈正相关(r=0.972、0.964、0.973，P<0.05)。三种方式测量角膜厚度的一致性分析为具有较好的一致性。

结论：A型超声角膜测厚、Allergro Oculyzer角膜地形图测厚、OCT角膜测厚三种测量方式对于CCT的测量具有明显的相关性和较好的一致性，临床上三种测量方式可以互为补充，相互参考。

METHODS:A total of 74 cases(148 eyes)were collected in the refractive surgery center in our hospital. The cornea thickness was measured by Germany Allegro Oculyzer; Germany Heidelberg OCT Spectralis and PachymetrySP-3000 respectively. The difference of CCT was compared using t-test, the correlation and agreement was analyzed among the three methods with Pearson-test and Bland-Altman-test.

Results: Mean CCT reading of Allegro Oculyzer; Heidelberg OCT Spectralis and PachymetrySP-3000 were 532.17±22.94μm, 526.53±24.52μm and 532.62±23.59μm. The t-test showed difference between Allegro Oculyzer and Pachymetry SP-3000(P<0.05). There was significant difference between Allegro Oculyzer and Heidelberg OCT Spectralis(P<0.05). There was no significant difference between Heidelberg OCT Spectralis and PachymetrySP-3000(P>0.05). There was significant linear correlation among the three methods(r=0.972, 0.964, 0.973; P<0.05). There was good agreement among the three methods.

CONCLUSION:CCT measured by Allegro Oculyzer; Heidelberg OCT Spectralis and PachymetrySP-3000 have high correlation and agreement. The three methods are complement of each other. All can be used in measurement of CCT.