方法：选取本院2015-06/2016-06收治的68例81眼非动脉炎性前部缺血性视神经病变(non-arteritic anterior ischaemic optic neuropathy，NAION)患者作为研究对象，按照年龄分为对照组36例39眼(平均年龄50岁以下)，观察组32例42眼(平均年龄50岁以上)。对两组患者的人口学特点、临床特点、相关危险因素、图形视觉诱发电位、视力等方面进行对比分析。

结果：对照组患者临床症状中，发病时有遮挡感、对侧眼受累比例均明显低于观察组患者，组间差异有统计学意义(P<0.05)。对照组患者1°空间频率和15'空间频率均明显优于观察组，组间差异有统计学意义(P<0.05)。对照组与观察组患者初始视力比较，差异无统计学意义(P>0.05)。对照组患者最终视力明显优于观察组患者，组间差异有统计学意义(P<0.05)。

结论：患有NAION的患者，其临床病症受年龄较大、发病时有遮挡感、对侧眼受累等因素影响，1°空间频率和15'空间频率延迟相对较严重，且最终视力并不十分良好。由此可见，对NAION患者进行电生理检查有助于进行病情的诊断，临床亦应该加强对NAION患者的随访，减少其患眼对侧眼的发病几率。

METHODS: Totally 68 cases(81 eyes)of NAION in our hospital from June 2015 to June 2016 were selected as the research object. All the subjects were divided into the control group(36 cases with 39 eyes), the observation group(32 cases with 42 eyes), according to the age, the age of the control group was at 50, the age of patients in the observation group was over 50. The demographic characteristics, clinical characteristics, risk factors, visual evoked potential and visual acuity of the two groups were compared and analyzed.

RESULTS: Clinical symptoms of the disease onset of the control group were occlusion, contralateral eye involvement, which was significantly lower than that of the patients in the observation group(P<0.05). Patients in the control group at 1° and 15 'spatial frequency were significantly better than those of the control group, there were obvious differences between groups(P<0.05). There was no significant difference between the control group and the observation group in the initial visual acuity(P>0.05). The final visual acuity of the control group was significantly better than that of the observation group(P<0.05).

CONCLUSION: For NAION patients, the clinical symptoms will be affected by age, occlusion, and contralateral eye involvement at the onset and other factors. The 1° and 15 'spatial frequency delay are relatively serious, and the final visual acuity is not very good. Thus, electrophysiological examination for the NAION patients help to diagnose the disease, clinicals should also strengthen the follow-up of NAION patients, reduce the contralateral eye.