方法：选取因糖尿病性视网膜病变于我院接受玻璃体切割手术并于术后出现角膜上皮缺损的患者20例20眼，随机分为两组：观察组10例10眼使用软性角膜接触镜联合成纤维细胞生长因子滴眼液、玻璃酸钠滴眼液点眼； 对照组10例10眼仅使用成纤维细胞生长因子滴眼液、玻璃酸钠滴眼液点眼。比较两组患者角膜上皮愈合的时间，同时对两组患者术后眼部舒适度进行比较评分。

结果：观察组患者角膜上皮愈合时间为4.1±1.20d，对照组患者角膜上皮愈合时间为14.2±6.07d，两组比较有统计学意义(P<0.05)。接受治疗后，观察组患者不舒适感明显减轻，对照组改观不明显，组间相比有统计学意义(P<0.05)。术后3mo，两组患者的眼部舒适度基本恢复到术前，组间比较无统计学意义(P>0.05)。

结论：软性角膜接触镜可以减轻角膜上皮缺损对患者造成的不适，缩短缺损修复的时间。

METHODS: Twenty patients(20 eyes)with diabetic retinopathy whose corneal epithelium defected after vitrectomy were randomly divided into 2 groups. The trial group(10 eyes)received the combination treatment of wearing soft corneal contact lenses and eyedrops to promote corneal epithelial repair, and the control group(10 eyes)only received eyedrops. The corneal epithelial healing time was observed postoperatively. And the scores of the comfort in patients between two groups were compared.

RESULTS: The average duration of corneal epithelial defects was 4.1±1.20d in the trial group, and 14.2±6.07d in the control group, which was statistically significant different between the two groups(P<0.05). After treatment, the patients in the trial group felt more comfortable compared with the ones in the control group. There was no significant statistical difference about the scores of the comfort between the two groups at postoperative 3mo(P>0.05).

CONCLUSION: The soft corneal contact lens could effectively treat patients with corneal epithelial defects after vitrectomy, and improve their comfort.