方法：选取2012-06/2015-09本院泪道阻塞患者200例200眼，进行泪道激光联合引流管植入术治疗，分别评估术前和术后1mo患者眼表情况，包括泪膜破裂时间、泪液羊齿状结晶、干眼症状问卷调查、丽丝胺绿染色、角膜荧光素染色等。

结果：经过泪道激光联合引流管植入术后1mo，患者眼表出现泪液的分泌量明显增加，拔管之后，患者泪液分泌量比术前明显减少差异有统计学意义(P<0.05)。问卷调查结果显示，患者在进行泪道激光联合引流管术后，流泪症状明显改善。手术前后以及拔管之后泪膜破裂时间、泪液羊齿状结晶评级、结膜杯状细胞均未见明显改变。

结论：泪道激光联合引流管植入术对泪道阻塞患者可以显著改善患者的流泪症状，提高其生活质量。

METHODS: Totally 200 patients(200 eyes)randomly selected from June 2012 to September 2015 in our hospital was diagnosed with lacrimal duct obstruction and treated with KTP laser combined drainage tube implantation. The ocular surface condition, including tear break-up time, fern-like crystals, dry eye symptoms questionnaire, lissamine green staining, corneal fluorescein staining, were assessed before and 1mo after surgery.

RESULTS: At 1mo after surgery, the tear secretion increased significantly. After extubation, tear secretion decreased significantly compared to the preoperative(P<0.05). The results of the questionnaire showed that the symptoms improved significantly after surgery. There were no significant differences between tear break-up time, fern-like crystals and conjunctival goblet cells before and after surgery, or after extubation.

CONCLUSION: KTP laser combined with drainage tube implantation can improve the symptoms and quality of life for lacrimal duct obstruction patients.