方法：采用前瞻性双盲随机对照临床研究。选取2014-01/2015-12在我院诊断为原发性翼状胬肉的患者140例140眼，随机分为A、B两组。A组患者(68例68眼)行连续锁边缝合，B组患者(72例72眼)行连续锁边缝合联合配戴角膜绷带镜。 比较两组患者的术后眼部疼痛程度评分、术后效果及并发症。

结果：A组患者术后1、3d，1wk眼部疼痛程度评分分别为1.62±0.71、0.83±0.52、0.31±0.36分，组内比较差异有统计学意义(F=8.60，P<0.01)，两两比较差异有统计学意义(P<0.01)； B组分别为0.98±0.47、0.27±0.14、0.12±0.21分，组内比较差异有统计学意义(F=13.60，P<0.01)，两两比较差异有统计学意义(P<0.01)，两组患者相同时间点比较，差异有统计学意义(t=6.23、8.56、7.03，P<0.05)； 术后1a时A组患者复发4眼，复发率为5.9%，B组患者复发4眼，复发率为5.6%，两组患者差异无统计学意义(P>0.05)； 术后随访1a，A组患者发生并发症10眼，发生率为14.7%，B组患者发生并发症3眼，发生率为4.2%，两组患者差异有统计学意义(χ² =4.61，P<0.05)。

结论：采用连续锁边缝合联合配戴角膜绷带镜治疗翼状胬肉可以促进角膜创面的修复，极大地减轻患者的术后刺激症状，减少术后并发症。

METHODS: A prospective randomized controlled double-blind study was conducted. Totally 140 cases(140 eyes)with pterygium were involved in the study from January 2014 to December 2015. All cases were randomly divided into two groups: 68 cases(68 eyes)in Group A received lock stitch suture, while 72 cases(72 eyes)in Group B received lock stitch suture with bandage contact lens. The postoperative reaction, effect, complications and so on were retrospectively analyzed between two groups.

RESULTS: One week later, the pain index scores at 1, 3 and 7d after surgery were 1.62±0.71, 0.83±0.52, 0.31±0.36 in Group A, and the pain index scores were 0.98±0.47,0.27±0.14, 0.12±0.21 in Group B, there were significant difference between the two groups(t=6.23, 8.56, 7.03, P<0.05), and the difference were statistically significant within Group A and B(F=8.60, 13.60, P<0.01); 4 of 68 eyes(5.9%)were recurrence after 1a in Group A and 4 of 72 eyes(5.6%)were recurrence in Group B, demonstrating no significant differences(P>0.05); 10 of 68 eyes(14.7%)with complications in Group A and 3 of 72 eyes(4.2%)with complications in Group B, demonstrating significant differences(χ²=4.61, P<0.05).

CONCLUSION: A good result can be obtained by using the lock stitch suture with bandage contact lens in the treatment of pterygium. The lock stitch suture with bandage contact lens could significantly release pain response, it can significantly reduce the probability of the concurrent appearance.