方法：选取我院门诊青少年近视患者150例，随机分为3组，A组50例为应用低浓度阿托品组，B组50例为验配角膜塑形镜组，C组50例为验配框架眼镜组。三组患者治疗前屈光度及眼轴长度差异无统计学意义。随访1a后通过统计学分析三组屈光度、眼轴长度变化。

结果：随访1a后各组屈光度治疗前后均有统计学意义(P<0.01)。各组间屈光度比较结果如下：低浓度阿托品组与角膜塑形镜组比较，差异无统计学意义(P>0.05)； 低浓度阿托品组与框架眼镜组比较，差异有统计学意义(P<0.05)； 角膜塑形镜组与框架眼镜组比较，差异有统计学意义(P<0.05)。随访1a后各组眼轴变化治疗前后均有统计学意义(P<0.01)。随访1a后各组间眼轴变化比较结果如下：低浓度阿托品组与角膜塑形镜组比较，差异无统计学意义(P>0.05)； 低浓度阿托品组与框架眼镜组比较，差异有统计学意义(P<0.05)； 角膜塑形镜组与框架眼镜组比较差异有统计学意义(P<0.05)。

结论：低浓度阿托品和角膜塑形镜在控制青少年近视度数增长，眼轴增长方面无明显差异，且两者控制青少年近视疗效均优于框架眼镜。

METHODS: Totally 150 cases of juvenile outpatients with myopia were chosen in our hospital. They were divided into 3 groups randomly. Group A(50 cases)were treated with low concentration atropine. Group B(50 cases)were treated with orthokeratology. Group C(50 cases)were treated with spectacles. Refractive degree and ocular axial length had no statistically significant differences between three groups before treatment. After 1a follow-up, refractive degree and ocular axial length of three groups were statistically analyzed.

RESULTS: After 1a, the refractive degree changes of each group before and after treatment were statistically significant(P<0.01). The results of refractive degree changes among the groups were as follows: there was no significant differences between low concentration atropine group and orthokeratology group(P>0.05); compared with orthokeratology and low concentration atropine group, that of spectacles group was significantly different(P>0.05). After 1a follow up, the ocular axial length changes of each group before and after treatment were statistically significant(P<0.01). The results of ocular axial length changes among the groups were as follows: there was no significant differences between low concentration atropine group and orthokeratology group(P>0.05); compared with orthokeratology and low concentration atropine group, that of spectacles group was significantly different(P<0.05).

CONCLUSION: The effects of low concentration atropine and orthokeratology on controlling juvenile myopia and ocular axial length have no significant difference. They are superior to spectacles on controlling juvenile myopia.