方法：选取2014-01/2015-12在我院行超声乳化白内障术后重度角膜水肿的患者68例68眼，其中男30例，女38例，年龄53～80(平均64.45±4.24)岁。按照治疗方式不同分为治疗组34例，给予常规治疗+高渗糖点眼联合局部给氧治疗； 对照组34例，常规治疗+高渗糖点眼治疗。治疗期间观察患者BCVA及角膜情况。

结果：治疗组患者角膜水肿消退时间平均为11.62±0.53d，对照组为15.23±0.62d，差异有统计学意义(P<0.05)。治疗前两组患者平均BCVA、角膜内皮细胞计数比较差异无统计学意义，组内比较两组治疗前后角膜内皮细胞计数比较差异具有统计学意义(P<0.05)。治疗后7d两组患者BCVA、角膜内皮细胞计数比较差异具有统计学意义(P<0.05)，治疗后1mo两组患者BCVA、角膜内皮细胞计数比较差异无统计学意义(P>0.05)。两组患者治疗有效率比较，差异具有统计学意义(P<0.05)。

结论：高渗糖点眼联合局部给氧治疗白内障术后角膜水肿的疗效显著。

METHODS: Totally 68 patients(68 eyes)with severe corneal edema after phacoemulsification were selected from January 2014 to December 2015 in our hospital, who were aged 53-80(64.45±4.24), including 30 males and 38 females. According to different treatment, they were divided into treatment group(34 cases)given conventional therapy + hypertonic sugar eyes drops with local to the oxygen therapy, the control group(34 cases)given conventional treatment + hypertonic sugar eyes drops. Visual acuity and corneal situation were observed during the treatment.

RESULTS: Corneal edema fade time of treatment group was 11.62+0.53d, that of control group was 15.23±0.62d, the difference between the two groups was significant(P<0.05). Preoperative best corrected visual acuity(BCVA)and corneal endothelial cell count had no significantly difference between the two groups while the corneal endothelial cell count were significantly different compared with postoperative of the two groups(P<0.05). At 7d after treatment, the BCVA and corneal endothelial cell count had significantly difference between the two groups(P<0.05), which did not have significant difference at 1mo after treatment(P>0.05). The effective rates of the two groups was significantly different(P<0.05).

CONCLUSION: Hypertonic sugar eyes drops with local to the oxygen therapy is effective for severe corneal edema after cataract surgery.