方法：回顾性分析2015-06/2016-09在我院诊治的特发性黄斑裂孔56例56眼，分别行25G+与27G+玻璃体切割术，各28例28眼，记录手术时间和术中并发症的发生情况。术后随访3～6mo，观察视力、眼压、黄斑裂孔愈合情况及并发症的发生情况，并对相关记录指标进行统计学分析。

结果：两组患者术后视力均较术前提高，差异有统计学意义(P<0.001)，两组之间比较差异无统计学意义(P=0.84)。无严重手术并发症发生。在手术时间、黄斑裂孔愈合率等方面两组病例差异无统计学意义(P=0.57、0.64)。术后第1d，27G+组低眼压(眼压<10mmHg)发生率小于25G+组，差异无统计学意义(P=0.31)。术后1wk，两组眼压与术前相比，差异均无统计学意义(P=0.72、0.92)。

结论：25G+与27G+玻璃体切割术治疗特发性黄斑裂孔均有较好的临床疗效，手术安全、有效。在维持眼压及减小手术切口创伤方面，27G+显示出较好的优越性。

METHODS: We retrospectively reviewed the clinical outcomes of 56 eyes(56 patients)with idiopathic macular hole which were treated with micro-incision vitrectomy from June 2015 to September 2016. Patients were divided into two groups, 28 patients(28 eyes)were treated with 25G+ vitrectomy and the rest(28 eyes)were treated with 27G+ vitrectomy. The operative time and intraoperative complications were recorded and patients were followed up for 3-6mo. During the follow up period, best correct vision acuity(BCVA), intraocular pressure, macular hole healing and postoperative complications were documented and statistically analyzed.

RESULTS: BCVA in two groups were significantly improved after surgery(P<0.001)and there was no significant difference between the two groups(P=0.84). No serious complications occurred. No statistically significant difference was found between the two groups in surgical time and healing rate of macular hole(P=0.57, 0.64). The incidence of low intraocular pressure(IOP<10mmHg)in 27G+ group was lower than that in 25G+ group on the first day after surgery(P=0.31). There was no significant difference between preoperative and postoperative intraocular pressure at 1wk after operation in both groups(P=0.72, 0.92).

CONCLUSION: Both 25G+ and 27G+ vitrectomy are safe and effective technique in treating idiopathic macular hole. Besides, 27G+ showed better superiority on the maintenance of intraocular pressure and reduce the trauma.