方法：采用描述性研究观察病例，收集2013-09/2016-03确诊为脾肾阳虚早期IMEM患者21例21眼，予温补并用之自拟中药固本明目散口服，疗程2mo，治疗前后均接受最佳矫正视力(best corrected visual acuity，BCVA)、对比敏感度检查，并参照中文版低视力者生活质量量表(Chinese-version Low Vision Quality of Life questionnaire，CLVQOL)，加以修改，比较治疗前后视觉变化给患者带来的生活影响。

结果：治疗后1、2、5mo时BCVA(LogMAR)分别为0.24±0.07、0.22±0.06、0.27±0.08，与治疗前(0.35±0.14)比较，有显著统计学差异(P<0.01)； 对比敏感度与治疗前相比，在6、12、18c/d空间频率均有提高， 差异具有显著统计学意义(P<0.01)，3c/d空间频率变化差异无统计学意义(P>0.05)； 治疗后夜间家中用眼时是否存在困难、看路标时是否存在困难、看电视小字时是否存在困难、因为目前视力对目前生活状态满意程度、对不能完成一些工作是否感到烦恼、对目前视力状况了解程度、使用助视器(或眼镜)后读书报容易程度等7项评分，与治疗前比较差异有显著统计学意义(P<0.01)。

结论：温补并用法能够改善IMEM患者的视觉功能，提高患者的生活质量。

METHODS: Totally 21 patients(21 eyes)diagnosed as early IMEM with spleen-kidney yang deficiency were treated by Gubenmingmu powder for 2mo. The best corrected visual acuity(BCVA), the contrast sensitivity and the modified vision quality of questionnaire score were detected to compare the life influence of pretherapy with posttherapy in visual changes.

RESULTS: The BCVA were separately 0.24±0.07、0.22±0.06、0.27±0.08 in the treating time of 1, 2 and 5mo. Contrast sensitivity function in special frequencies of 6,12 and 18c/d increased than pretherapy(P<0.01), those of 3c/d were no statistically significant(P>0.05). Scales of night fixation difficulty, guidepost difficulty, TV font difficulty, satisfaction, annoyance, understanding, newspaper easiness had significant differences(P<0.01), while the rest of the scales had no significant differences(P>0.05).

CONCLUSION: The TCM warm-reinforcing method could improve the visual function of IMEM patients and improve patients' quality of life.