方法：选取我院在2015-03/2016-03收治的糖尿病患者超乳术后角结膜干燥症患者78例78眼作为研究对象，使用随机数字表法分为两组，A组应用普拉洛芬滴眼液+人工泪液+芪明颗粒治疗39眼，B组应用普拉洛芬滴眼液+人工泪液治疗39眼。观察并比较两组患者治疗前后的临床症状、泪眼破膜时间、角膜荧光素染色结果、不良反应等情况。

结果：A组患者的治疗总有效率为97%，显著高于B组的64%，差异有统计学意义(P<0.05)。治疗后，两组的症状及体征评分均明显降低，泪膜破裂时间均明显延长，并且A组治疗后1、2wk，1mo的临床症状及体征评分均显著低于B组，泪膜破裂时间均显著长于B组，差异有统计学意义(P<0.05)。A组治疗后2wk的荧光素染色评分显著低于B组，差异有统计学意义(P<0.05)。

结论：普拉洛芬滴眼液+人工泪液+芪明颗粒治疗糖尿病患者超乳术后角结膜干燥症，能够迅速、有效地改善临床症状及体征，临床疗效确切，且无严重不良反应。

METHODS: Totally 78 diabetic patients 78 eyes with keratoconjunctivitis sicca(KCS)after phacoemulsification from March 2015 to March 2016 were selected and divided into two groups using random number table. In Group A, 39 eyes were treated with pranoprofen eye drops + artificial tears + Qiming granules. In Group B, 39 eyes were treated with pranoprofen eye drops + artificial tears. the two groups were observed for clinical symptoms, tear film break up time(BUT), corneal fluorescein staining and adverse reaction and so on before and after treatment.

RESULTS: Total effective rate of Group A was 97%, significantly higher than that of Group B(64%)(P<0.05). After treatment, symptoms and signs scores of the two groups were significantly lower, BUT were significantly prolonged. At 1, 2wk and 1mo after treatment, symptoms and signs scores of Group A were significantly lower the BUT was longer than those of Group B(P<0.05). Corneal fluorescein staining of Group A at 2wk was lower than that of Group B(P<0.05).

CONCLUSION: The combined therapy, pranoprofen eye drops + artificial tears + Qiming granules, is able to quickly and effectively improve the clinical symptoms and signs, with no serious adverse reactions for keratoconjunctivitis sicca after phacoemulsification in patients with diabetes.