方法：这是一项病例对照研究，于2015年在Birjand进行。研究的样本量确定为304例(计算机用户组和对照组每组152例)。两组都使用非随机抽样方法。泪液分泌试验用于评价研究对象的干眼情况。研究对象填写问卷，所用问卷通过回顾文献基于客观情况发展来。使用SPSS进行卡方检验和Fisher检验，显著性水平为0.05。

结果：干眼发生率：对照组为3.3%(5例)，计算机用户组为61.8%(94例)。两组差异具有统计学意义(P<0.01)。眼部不适症状发生率：对照组为7.9%(12例)，计算机用户组为34.2%(52例)，两组之间的差异具有统计学意义(P<0.01)。计算机用户组，不同性别、不同年龄之间干眼发生率无统计学差异(P=0.8)。干眼患者平均每天使用计算机时间为6.65±3.52h，对照组为1.62±2.54 h(T=13.25， P<0.001)。

结论：这一研究显示了使用计算机和干眼、眼部症状发生具有显著相关性。因此，管理人员需要对员工使用计算机工作的时间予以特别的关注。

METHODS: This study was a case control research conducted in 2015 in the city of Birjand. Sample size of study was estimated to be 304 subjects(152 subjects in each group, computer user group and control group). Non-randomized method of sampling was used in both groups. Schirmer test was used to evaluate dry eye of subjects. Then, subjects completed questionnaire. This questionnaire was developed based on objectives and reviewing the literature. After collecting the data, they were entered to SPSS Software and they were analyzed using Chi-square test or Fisher's test at the alpha level of 0.05.

RESULTS: In total, 304 subjects(152 subjects in each group)were included in the study. Frequency of dry eyes in the control group was 3.3%(5 subjects)and it was 61.8% in computer users group(94 subjects). Significant difference was observed between two groups in this regard(P<0.001). The frequency of eye symptoms in the control group was 7.9%(n=12), and it was 34.2% in computer users group(n=52), which significant difference was observed between two groups in this regard(P<0.001). Frequency of dry eye syndrome in computer users by gender and age groups showed no significant correlation in this regard(P=0.8). The mean working hour with computer per day in patients with dry eye was 6.65±3.52h, while it was 1.62±2.54h in healthy group(T=13.25, P<0.001).

CONCLUSION: This study showed a significant relationship between using computer and dry eye and ocular symptoms. Thus, it is necessary that officials need to pay particular attention to working hours with computer by employees. They should also develop appropriate plans to divide the working hours with computer among computer users. However, due to various confounding factors, it is recommended that these factors to be controlled in future studies.