目的：比较眼睑加热联合眼睑按摩与人工泪液对办公室干眼的疗效。

方法：本研究纳入办公室工作人员干眼患者60例60眼，并随机分为2组。对照组给予人工泪液治疗，试验组给予蒸汽润眼仪联合眼睑按摩治疗。所有受检者均在治疗前、治疗后2、4wk按照以下顺序进行检查：眼表疾病指数问卷表、泪膜破裂时间、角膜荧光素染色、Schirmer I试验与睑板腺分泌功能评估。

结果：入选60例60眼干眼患者中，48例48眼患者(对照组23例23眼，试验组25例25眼)患有睑板腺功能障碍。4wk的治疗过程中，眼表疾病指数评分(F_分组=41.63，P<0.01)、泪膜破裂时间(F_分组=60.47，P<0.01)与睑板腺分泌物性质评分(F_分组=12.12，P<0.01)，实验组疗效均优于对照组。角膜荧光素染色(F_分组=1.79，P>0.05)、泪液分泌量(F_分组=0.17，P>0.05)与睑板腺管通畅率评分(F_分组=0.68，P>0.05)，两组间差异无统计学意义。

结论：睑板腺功能障碍是我国办公室干眼的重要病因，眼睑加热联合眼睑按摩对办公室工作人员干眼疗效优于人工泪液。

METHODS: Sixty ODE patients were recruited, and these patients were randomly divided into two groups. One group received artificial tear treatment, and the other group received a new eyelid warm moist air device combined with eyelid massage treatment. Subjects completed the ocular surface disease index(OSDI), which was followed by fluorescein tear breakup time(BUT), corneal fluorescein staining(CFS), Schirmer I test(SⅠt)and meibomian gland secretion function evaluation at baseline, and 2 and 4wk after treatment.

RESULTS: In these 60 patients, 48 patients(23 in artificial tear treated group and 25 in the new warm moist air device assisted with eyelid massage treated group)were positive for meibomian gland dysfunction(MGD). Compared to artificial tear treatment, the new warm moist air device assisted with eyelid massage treatment showed favorable therapeutic effect on OSDI(F_Group=41.63, P<0.01), BUT(F_Group=60.47,P<0.01)and the grade of meibum quality(F_Group=12.12,P<0.01)during 4wk treatment in this study. No significant difference was found in SIT(F_Group=0.17, P>0.05), CFS(F_Group=1.79, P>0.05)and meibomian gland expressibility(F_Group=0.68, P>0.05)between the two groups during 4wk treatment.

CONCLUSION: This new eyelid warm moist air device assisted with eyelid massage has favorable therapeutic effect over artificial tear in ODE treatment.