目的：探究2型糖尿病患者糖尿病视网膜病变(DR)的严重度及受试者中糖尿病视网膜病变严重程度与其病程、糖化血红蛋白水平、高血压史、年龄和性别的相关性。

方法：横断面研究。2012-05/06，采取简单随机抽样方法进行结构化问卷调查，收集100例年龄≥35岁糖尿病视网膜病变患者。进行描述性统计、单变量和多变量有序逻辑回归分析。用excel表进行数据录入，并用SPSS 21.0进行数据分析(P<0.05)。

结果：100例患者，平均年龄53.16±10.81(35～78)岁。通过单因素分析发现，糖尿病视网膜病变严重度与年龄(P<0.01)，糖尿病病程(P<0.001)，糖化血红蛋白水平(P<0.001)，糖尿病家族史(P<0.01)，高血压病史(P<0.05)，均呈正相关，高密度脂蛋白(HDL)及年龄与DR严重程度无相关性。除年龄因素外，上述所有因素均为影响糖尿病视网膜病变严重度的独立风险因素。

结论：研究表明，糖尿病病程、糖化血红蛋白水平、糖尿病家族史、高血压病史以及性别与糖尿病视网膜病变严重程度密切相关。但多因素分析中，年龄、HDL因素与DR严重程度无关。因此，利用现有治疗手段的有效性和及时控制，可以预防和消除视力威胁性疾病，延缓DR的发生。

AIM:To find the severities status of diabetic retinopathy(DR)among the patients with type 2 diabetes mellitus and to determine the association of the severities of diabetic retinopathy with duration of DR, HbA1C levels, history of hypertension, age and gender in the study population.

METHODS:Hospital based cross-sectional studies with sample of 100 patients with DR were selected by using simple random sampling technique with a structured questionnaire was conducted in May to June 2012. The study participants those who with DR aged ≥35 years were included in this study and an oral consent was also collected from the study participants. Descriptive statistics, univariate and multivariate ordinal logistic regression analysis were performed. MS Excel spread sheet was used for data entry and data analysis was done by using SPSS 21.0 version. Statistical significance was taken as P<0.05.

RESULTS:Out of 100 patients, mean age of the patient was found as 53.16±10.81(range 35-78)y. By univariate analysis, there was a positive relationship between diabetic retinopathy severity and age(P<0.01), duration of DM(P<0.001), HbA1C levels(P<0.001), history of hypertension, family history of DM(P<0.05)were highly significant, high density lipoprotein(HDL)(mmol/L)and age were not significant with P>0.05 by Mann Whitney u-test. All these factors were found as independent risk factors with the severity of DR except the factor age.

CONCLUSION:This study was concluded that the duration of DM, HbA1C levels, family history of DM, History of hypertension and gender were independently associated with severity of DR. However, the factors like age and HDL weren't significant with severity of DR in multivariate analysis. Therefore, by using the availability of the existing treatments and controlling in time, which can prevent and free from the vision threatening diseases or delay the occurrence of DR in their life.