方法：选取2015-02/08行白内障超声乳化联合人工晶状体植入术的干眼患者90例90眼，随机分为小牛血去蛋白提取物眼用凝胶组(A组)、玻璃酸钠滴眼液组(B组)和维生素A棕榈酸酯眼用凝胶组(C组)，每组30例30眼。分别于术前，术后7、30、90d进行干眼问卷调查(OSDI)、泪膜破裂时间检查(BUT)、角膜荧光染色(FL)、泪液分泌试验(SⅠt)、睑板腺照相。

结果：三组各项检查值在术前无统计学差异(P>0.05)，组内各项检查术前与术后7、30、90d比较，除睑板腺评分，差异无统计学意义(P>0.05)，其他各项检查差异均有统计学意义(P<0.05)。术后7d，各组SⅠt、BUT检查低于术前，FL、OSDI评分高于术前差异均有统计学意义(P<0.05)，各组间差异无统计学意义(P>0.05)。术后30d，SⅠt、BUT及OSDI评分结果A、C组优于B组，差异有统计学意义(P<0.05)，FL检查结果A组优于B、C组，差异有统计学意义(P<0.05)，术后30、90d，三组SⅠt、BUT、FL、OSDI评分均较术前均有不同程度改善，差异有统计学意义(P<0.05)，术后90d，三组各项检查结果两两比较差异无统计学意义(P>0.05)。

结论：超声乳化手术会影响干眼患者泪膜稳定性及睑板腺功能，局部应用小牛血眼用凝胶、玻璃酸钠滴眼液和维生素A棕榈酸酯眼用凝胶均可改善干眼患者的症状。小牛血去蛋白提取物眼用凝胶和维生素A棕榈酸酯眼用凝胶在延长BUT方面优于玻璃酸钠，小牛血去蛋白提取物眼用凝胶修复角膜上皮方面更具优势。

METHODS: All 90 cataract patients(90 eyes)with preoperative dry eye who underwent phacoemulsification randomly divided into three groups(Group A treated with protein-free calf blood extract ophthalmic gel; Group B treated with sodium hyaluronate eye drops; Group C treated with Vitamin A palmitate eye gel). Ocular Surface Disease Index(OSDI), Schimer's I test(SⅠt), tear film break time(BUT), corneal fluorescein staining(FL)and meibography were performed for all patients preoperatively and 7, 30 and 90d postoperatively.

RESULTS: No statistical differences existed among the three preoperative groups(P>0.05). Except meibomian gland score, there was no statistical significance among preoperatively and 7, 30, 90d postoperatively of the three groups(P>0.05). At 7d postoperatively, SⅠt and BUT of every group were lower than those before treatment, FL scores and OSDI scores were higher than those preoperative(P<0.05); there were no statistical differences among the three groups(P>0.05). At 30d postoperatively, SIt, BUT, OSDI scores in group A and C were better than in group B, which displayed statistical differences(P<0.05); FL scores in group A were significantly better than in group B and C(P<0.05). At 30, 90d postoperatively, SIt, BUT, FL scores, OSDI scores were better than preoperative results, which displayed statistical differences(P<0.05). There were no statistical differences among the three groups at 90d postoperatively(P>0.05).

CONCLUSION: Tear film stability and meibomian gland function were affected by phacoemulsification. Topical application of deproteinised calf blood extract eye gel, sodium hyaluronate eye drops and Vitamin A palmitate eye gel all hase a clearly beneficial effect on subjective symptoms. Deproteinised calf blood extract eye gel and Vitamin A Palmitate Eye Gel had more powerful effect on BUT than sodium hyaluronate, however deproteinised calf blood extract eye gel is more effective in superficial punctuate keratopathy.