目的：比较白内障超声乳化手术中复方电解质液和乳酸林格氏液对角膜功能的影响，为临床选择适宜的灌注液提供科学依据。

方法：收集老年性白内障患者随机分为以乳酸林格氏液为前房灌注的对照组和以复方电解质液为前房灌注液的试验组。术式为白内障超声乳化手术摘除伴人工晶状体植入术。分别在术前、术后各随访点测量角膜内皮细胞密度、中央角膜厚度、视力、角膜水肿、六角形细胞比例和内皮细胞变异系数等。

结果：患者60例60眼顺利完成术后随访，试验组30例30眼，对照组30例30眼。两组患者术后1、3d复方电解质液组角膜内皮细胞密度大于乳酸林格氏液组角膜内皮细胞密度，两组间差异有统计学意义(P=0.030、0.046)。术后1、14d，乳酸林格氏液组角膜内皮细胞变异系数与复方电解质液组比较，两者差异有统计学意义(P=0.025、0.014)。复方电解质液组患者术后第1d视力优于乳酸林格氏液组，差异有统计学意义(P=0.040)。

结论：在老年性白内障超声乳化手术中，复方电解质灌注液有较好的组织相容性，可以更好地维持角膜内皮细胞结构的稳定，减轻角膜内皮细胞的损伤； 复方电解质灌注液较乳酸林格氏液更适用于老年性白内障超声乳化手术。

METHODS: The patients with senile cataract were randomly divided into control group with lactated Ringer's solution as anterior chamber perfusion and experimental group with compound electrolyte as anterior chamber perfusion. Surgical removal of cataract and phacoemulsification with intraocular lens implantation were taken. The corneal endothelial cell density, central corneal thickness, hexagonal cell ratio and endothelial cell coefficient of variation were measured at preoperative and postoperative points.

RESULTS: Totally 60 patients successfully completed all follow-ups, the experimental group of 30 cases, the control group of 30 cases. The density of corneal endothelial cells in experimental group was significantly higher than those in the lactated Ringer's solution group at 1 and 3d after operations(P=0.030, 0.046). The coefficient of variation of corneal endothelial cells in lactated Ringer's solution group was higher than that in compound electrolyte group at 1 and 14d after operation(P=0.025, 0.014). The visual acuity of the compound electrolyte group was better than that of the lactated Ringer's solution on the first day after operation(P=0.04).

CONCLUSION: In the phacoemulsification of senile cataract, the compound electrolyte perfusion has better histocompatibility, which can maintain the stability of corneal endothelial cell structure and reduce corneal endothelial cell injury. The compound electrolyte perfusion solution is more suitable for senile cataract phacoemulsification surgery.