目的：检查一组正常青少年高加索人群视网膜各项指标，以确定该年龄段和种族群体双眼之间不对称性的正常范围。

方法：所研究人群包含37名高加索儿童和青少年，年龄12～23岁，等效球镜-3.00D～+4.00D，屈光参差<0.5D，两眼之间眼轴差<0.3mm。检测正常两眼各指标之间不对称性数值和两眼之间差异容许值的95%范围。

结果：所有受试者左眼检测数值更大，两眼之间平均视网膜神经纤维(RNFL)厚度和上方RNFL厚度差异有统计学意义(P=0.003， 0.008)，中央黄斑厚度也存在显著差异(P=0.039)。检测得出以上三项两眼之间不对称性容许范围分别-9.00～6.00μm、-28.00～9μm、-39.00～29.00μm。此外，男性和女性之间右眼平均RNFL厚度的差异有统计学意义(P=0.020)。

结论：两眼之间视网膜检测数值不对称性正常范围的研究可能是更进一步了解近视发生和发展的有效方法。这对于该年龄段的人群十分重要。检测仪器和检测人群特征的不同限制了研究结果和已发表文献的直接比较，需要进一步研究。

METHODS: Study sample consisted of 37 Caucasian children and young adults aged between 12 and 23 years(spherical equivalent from -3.00D to +4.00D, anisometropia <0.5D and axial length differences <0.3mm). Normal inter-ocular asymmetry values were determined and 95% inter-ocular difference tolerance values were obtained.

RESULTS: Statistically significant inter-ocular differences were found in mean(P=0.003)and superior(P=0.008)retinal nerve fiber layer(RNFL)thickness, as well as in central macular thickness(P=0.039), with larger values in the left eye in all instances, and with tolerance limits of inter-ocular asymmetry of -9.00μm to 6.00μm, -28.00μm to 9μm and -39.00μm to 29.00μm, respectively. In addition, statistically significant differences were found between males and females in mean thickness of the RNFL in the right eye(P=0.020).

CONCLUSION: The exploration of the normal asymmetries of the retina may be an effective approach to further understand myopia onset and progression, which is particularly relevant in this age group. Differences in instrumentation and sample characteristics compromise direct comparison with published research and warrant the need for further studies.