目的：探讨23G玻璃体切割术治疗白内障术后迟发型眼内炎的临床疗效。

方法：回顾性分析2010-01/2016-01在武汉大学人民医院，接受23G玻璃体切割术治疗的白内障术后迟发型眼内炎患者15例15眼，距离白内障手术的平均时间为5.13±2.41mo。患者术前均有不同程度眼内炎症状及体征，术后行眼前段、眼底及最佳矫正视力检查。

结果：致病菌培养结果显示，致病菌培养阳性9眼(60%)，由厌氧菌感染引起4眼(44%)，由真菌感染引起3眼(33%)，由需氧菌感染引起2眼(22%)。术后的平均随访时间为12mo。经23G玻璃体切割术治疗后，与治疗前视力比较，差异有统计学意义(P=0.009)，经23G玻璃体切割术联合人工晶状体取出、硅油填充及晶状体囊切割治疗后炎症未得到有效控制，行眼内容物剜除术1眼(7%)。

结论：23G玻璃体切割术治疗白内障术后迟发型眼内炎安全、有效，联合人工晶状体取出及晶状体囊切割可能有效预防其复发。

METHODS: This retrospective chart review study included patients with delay-onset endophthalmitis that was present 6wk or more after cataract surgery, who underwent 23-gauge PPV from January 2010 to January 2016 at Renmin Hospital of Wuhan University. The diagnosis was made according to clinical symptoms and signs. The postoperative follow-up results were recorded, including anterior segment examinations, fundus examinations, and best-corrected visual acuity.

RESULTS: Totally 15 patients(15 eyes)were included. The average time between cataract surgery and their eye symptoms of endophthalmitis was 5.13±2.41mo. The culture isolates revealed that 9 eyes(60%)were cultured positive, anaerobes in 4 eyes(44%), fungal infections in 3 eyes(33%), aerobes in 2 eyes(22%). The mean follow-up period was 12mo. The final visual outcomes were as follows: 11 eyes(73%)achieved a better vision with PPV; 3 eyes(20%)achieved a better vision with PPV, total capsulectomy(TC)and IOL removal; 1 eye(7%)with PPV, silicone oil tamponade, total capsulectomy(TC)and IOL removal was enucleated because of uncontrolled inflammation.

CONCLUSION: The 23-gauge PPV is safe and effective for the management of delay-onset endophthalmitis following cataract surgery. Recurrence rate might be decreased with total capsulectomy and IOL removal.