目的：评估正常眼和圆锥角膜眼的角膜高阶像差(HOAs)。

方法：使用OPD-Scan Ⅱ波前像差分析仪，评估80例80眼圆锥角膜(KC)患者和91例正常眼角膜表面参数。对两组受试者的Zernike系数第三阶到第六阶，原始彗差均方根(RMS)，彗差和总高阶像差进行比较分析。

结果：圆锥角膜眼和正常眼间测得的像差具有显著差异(P<0.001)，相较于正常眼，圆锥角膜患者像差参数显著较高(P<0.001)。

结论：通过OPD-Scan Ⅱ测量角膜波前像差在圆锥角膜眼中显著高于正常眼。

METHODS: Using an OPD-Scan Ⅱ wavefront analyzer, aberrometric parameters of the corneal surface in one eye of 80 patients with keratoconus(KC)and 91 participants with normal eyes were evaluated. The Zernike coefficients from third- to sixth-order as well as root mean square(RMS)of primary coma, coma-like aberrations, and total HOA were calculated and compared between both groups.

RESULTS: Statistically significant differences were found in all aberrometric parameters between the measurements of the KC and normal participants(P<0.001). All of the aberrometric parameters were significantly higher in the KC patients compared to the normal group(P<0.001).

CONCLUSION: Corneal wavefront measurements by means of OPD-Scan Ⅱ were significantly higher in keratoconic corneas than normal corneas.