目的：分析儿童多发性睑板腺囊肿的相关危险因素。

方法： 选取2013-02/2015-02在我科就诊的资料完整的300例600眼多发性睑板腺囊肿患儿(试验组)和236例472眼条件类同的眼科体检正常儿童(对照组)进行病例对照研究，采用Logistic回归方法进行多因素分析，筛出主要危险因素。

结果：经Logistic回归分析，发现睑板腺功能、泪液分泌减少、家族史、便秘、偏食、居住环境与儿童多发性睑板腺囊肿的发生显著相关。而视力、血液胆固醇、微量元素、细菌感染与疾病无显著相关。

结论：睑板腺功能、泪液分泌减少、家族史、便秘、偏食、居住环境等为儿童多发性睑板腺囊肿的主要危险因素。应重视并针对其危险因素加以预防。

METHODS: In experimental group, 300 cases(600 eyes)of children with multiple chalazion and the control group, 236 cases(472 eyes)of similar eye examination of the normal children in case-control studies, using Logistic regression method to analyze many factors to screen out the main risk factors.

RESULTS: By Logistic regression analysis, we found the meibomian gland function, tear secretion reduces, family history, constipation, partial eclipse, living environment were correlated with the occurrence of multiple meibomian gland cyst in children, and no significant correlation with visual acuity, blood cholesterol, trace elements, and bacterial infection.

CONCLUSION: The meibomian gland function, tear secretion reduce, family history, constipation, partial eclipse, living environment for children, are main risk factors for multiple chalazion. We should pay attention to those factors to prevent it.