目的：系统评价中医理疗联合托吡卡胺滴眼液治疗儿童及青少年假性近视的疗效。

方法：计算机检索2000/2015年中国期刊网全文数据库(CNKI)、中国生物医学文献数据库(CBM)、万方全文数据库、美国医学文摘数据库(PubMed)、EMBASE、Cochrane Library，收集关于中医综合疗法联合托吡卡胺滴眼液治疗假性近视与常规托吡卡胺滴眼液治疗假性近视疗效比较的随机对照试验(randomized controlled trial，RCT)，采用改良Jadad评分量表对纳入文献的研究方法学进行评分，提取数据，采用Review Manager 5.3统计学软件进行Meta分析。

结果：共有5篇符合检索纳入标准的文献纳入分析，总样本量836例。Meta分析显示中医理疗联合托吡卡胺滴眼液治疗假性近视的疗效明显优于对照组，差异有统计学意义(Z=6.39，P<0.01)。

结论：与单纯使用托吡卡胺滴眼液相比，联合中医理疗更能有效地治疗儿童及青少年假性近视，且安全可靠。

METHODS: We collected randomized controlled trials from CNKI, CBM, Wanfang database, PubMed, EMBASE and Cochrane Library in 2000-2015, and the improved Jadad scale was used to evaluate the methodology of the literature, and the data was extracted. The Review Manager 5.3 statistical software was used for meta analysis.

RESULTS: A total of 5 articles were included in the analysis, with a total sample size of 836 cases. The curative effect of experimental group on pseudomyopia was better than that of control group, and the differences are statistically significant(Z=6.39, P<0.01).

CONCLUSION: Compared with topiramine eye drops alone, combined with traditional Chinese medicine therapy for treating pseudomyopia in children and adolescent is more effective, and is safe and reliable.