目的：探讨妊娠高血压视网膜病变发生的危险因素，分析其对母婴妊娠结局的影响。

方法：选取符合研究筛选要求的妊娠高血压患者100例作为研究对象，分为无视网膜病变组(29例)和视网膜病变组(71例)，对两组患者年龄、病程、孕周、血压、蛋白尿和红细胞压积等变量进行单因素分析，通过Logistic回归分析探讨独立危险因素，同时分析妊娠高血压视网膜病变母婴妊娠结局的影响。

结果：单因素分析结果表明，除年龄外，患者病程、孕周、血压、蛋白尿和红细胞压积等比较，差异均具有统计学意义(P<0.01)； Logistic回归分析结果表明，病程、血压、蛋白尿和红细胞压积均是视网膜病变发生的危险因素，孕周是保护因素； 与无视网膜病变组相比，视网膜病变组患者发生早产、胎盘早剥、产后出血、围生儿死亡风险显著升高，差异有统计学意义(P<0.01)，其增加幅度与视网膜病变等级存在一定相关性。

结论：妊娠高血压患者病程、血压、蛋白尿及红细胞压积是视网膜病变发生的危险因素，视网膜病变发生会对母婴妊娠结局产生严重不良影响。

METHODS: A total of 100 patients with gestational hypertension who met the requirements of screening were selected, they were divided into two groups, without retinal lesion group(n=29)and retinopathy group(n=71). The age, course of disease, gestational age, blood pressure, proteinuria and hematocrit in two groups were investigated. The risk factors were detected by single factor analysis, and then the study on independent risk factors were analyzed by Logistic regression analysis. At the same time, their influence on maternal and child pregnancy outcomes were investigated.

RESULTS: The single factor analysis showed that except for age, the differences in the course of disease, gestational age, blood pressure, proteinuria and hematocrit were statistically significant(P<0.01). Logistic regression analysis showed that the course of disease, blood pressure, proteinuria and hematocrit were the risk factors of retinopathy, gestational age was a protective factor. Compared with the group without retinopathy, the incidence of preterm birth, placental abruption, postpartum hemorrhage, perinatal death in the patients with retinopathy significantly increased, and the difference were statistically significant(P<0.01), and there was a certain correlation between the extent of increase and the grade of retinopathy.

CONCLUSION: Course of disease, blood pressure, proteinuria and hematocrit of patients with the hypertension of pregnancy are the risk factors of retinopathy, retinopathy has a serious adverse effect on maternal and child pregnancy outcomes.