目的：应用双通道视觉质量分析系统评价V4c型可植入式隐形眼镜(implantable contact lens V4c，ICL V4c)植入术矫正高度近视眼的术后视觉质量及有效性。

方法：采用前瞻性系列病例研究。选取近视度数为-6.00～-12.00D患者30例60眼，年龄18～35岁，术前最佳矫正视力≥0.6，角膜散光≤1.0D，全部采取颞侧透明角膜切口，植入ICL V4c后房型人工晶状体，分别在术后1wk，1、3mo进行随访观察，检查项目：术前最佳矫正视力(BCVA)、术后裸眼视力(UCVA)、术眼的OSI(客观散射指数)、MTF cut off(调制传递函数截止频率)、SR(斯特列尔比值)和100%、20%及9%的OV值(对比度视力)。应用SPSS19.0 统计学软件进行数据处理，手术前后各项参数比较采用重复测量数据的方差分析。

结果：术后1wk，1、3mo的UCVA逐渐改善，与术前BCVA比较均有统计学意义(P<0.01)。术后1wk，1、3mo的OSI、MTF cut off、SR、OV 100%、OV 20%及OV 9%均优于术前，与术前比较均有统计学意义(P<0.05)。

结论：ICL V4c植入术能有效矫正-6.00～-12.00D的高度近视，术后OSI比术前减小，术后UCVA优于术前BCVA，术后的MTF cut off、SR、100%、20%、9%的OV值比术前均有提高。

METHODS: Totally 60 eyes of 30 high myopia patients who underwent ICL V4c implantation were enrolled into this prospective randomized control study. Myopic degree of selected patients was -6.0D to -12.0D, age 18 to 35 years old, best corrected visual acuity(BCVA)≥0.6, preoperative corneal astigmatism acuities ≤1.0D. All patients were taken the temporal side transparent corneal incision. The patients were evaluated postoperatively 1wk, 1 and 3mo respectively. The evaluating items included preoperative BCVA, postoperative uncorrected visual acuity(UCVA), objective scattering index(OSI), and modulation transfer function(MTF)cut off frequency, Strehl ratio(SR), and 100%, 20%, 9% Optical Quality Analysis System(OQAS)Value(OV, contrast visual acuity). All statistical analyses were performed with SPSS19.0 statistical software. Variance analysis of repeated measurement data was employed.

RESULTS: The UCVA gradually improved at 1wk, 1 and 3mo after surgery. There was statistical significance compared with the preoperative BCVA(P<0.01). The postoperative OSI, MTF cut off, SR, OV 100%, OV 20% and OV 9% at 1wk, 1 and 3mo showed statistically differences compared with the preoperative values(P<0.05).

CONCLUSION: ICL V4c implantation can effectively correct high myopia range from -6.0D to -12.0D. The postoperative OSI were smaller than the preoperative OSI. The postoperative UCVA were better than the preoperative BCVA. The value of postoperative MTF cut off, SR, and OV value of 100%, 20% and 9% improved.