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[摘要]
目的:评估翼状胬肉患者中过敏性疾病流行情况和皮肤针刺试验阳性率。
方法:62例翼状胬肉患者与年龄性别匹配的相同数量健康受试者纳入了这项研究。所有患者和健康受试者均接受眼科医生和过敏性疾病专科医生检查。皮肤针刺试验检测了常见致敏原。血清总IgE使用ELISA检测。
结果:过敏性鼻结膜炎在翼状胬肉患者中更多(19.3% vs 3.2%, P=0.002),但是在其他过敏性疾病或过敏症状上的差异没有统计学意义。皮肤针刺试验中,翼状胬肉患者对至少一种致敏原阳性的比率显著高于健康人(38.7% vs 6.5%, P=0.003)。蟑螂和尘螨是所调查翼状胬肉患者中最常见的致敏原(16.1%、12.9%)。
结论:本研究发现翼状胬肉患者中鼻结膜炎和皮肤针刺试验阳性率均较正常人高。
[Key word]
[Abstract]
AIM: To evaluate the prevalence of allergic disorders and skin prick test sensitivity to different allergens among patients with pterygium.
METHODS: Sixty two patients with pterygium and equal number of age/ sex matched healthy controls were enrolled in this study. All patients and controls examined by an ophthalmologist and allergist. Skin prick test performed with a battery of common allergens and serum total IgE level determined by ELISA method.
RESULTS: Prevalence of allergic rhinoconjunctivitis was significantly higher in patient group(19.3% vs 3.2%, P=0.002)but there was no significant differences in other allergies and symptoms between two groups. The rate of skin reactivity to at least one allergen was significantly higher in pterygium group than healthy controls(38.7% vs 6.5%, P=0.003). Cockroach and house dust mites were the most prevalent allergens among patients(16.1% and 12.9%).
CONCLUSION: The results of current study showed higher prevalence of rhinoconjunctivits and skin prick sensitivity to allergen among pterygium patients. This may has implication in prevention and treatment of pterygium.
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