目的：探讨玻璃棒法按摩睑板腺与常规疗法联合治疗睑板腺功能障碍(MGD)的临床疗效。

方法：回顾性分析2016-08/2017-06我院收治的MGD患者130例220眼，根据治疗方式不同进行分组，其中给予常规治疗即1g/L氟米龙滴眼液联合自行热敷的患者设为对照组(65例112眼)，给予圆头玻璃棒按摩睑板腺联合常规疗法的患者设为联合组(65例108眼)。比较两组患者治疗前后眼表疾病指数量表(OSDI)评分、泪膜破裂时间(BUT)、基础泪液分泌试验(SⅠt)、角膜荧光素染色(CFS)评分、睑缘评分、睑板腺分泌物性状评分和眼压情况及临床治疗有效率。

结果：治疗前，两组患者OSDI评分、BUT、SⅠt、CFS评分、睑缘评分、睑板腺分泌物性状评分、眼压情况差异均无统计学意义(P>0.05)。治疗2wk后，联合组患者OSDI、CFS、睑缘及睑板腺分泌物性状评分均低于对照组，BUT和SⅠt均大于对照组，差异均有统计学意义(P<0.01)； 两组患者眼压均有所升高，但均≤21mmHg，两组间差异无统计学意义(P>0.05)。治疗2wk后，联合组总有效率为92.6%(100/108)，对照组总有效率为78.6%(88/112)，差异具有统计学意义(P<0.05)

结论：玻璃棒法按摩睑板腺与常规疗法联合治疗MGD能够有效改善眼表症状和睑板腺分泌功能，促进泪液分泌，提高临床治疗有效率。

METHODS: Totally 130 cases(220 eyes)of MGD treated in our hospital from August 2016 to June 2017 were analyzed retrospectively. The combined group(n=65, 108 eyes)were treated with glass rod massage combined with conventional Meibomian gland dredging; controlled group(n=65, 112 eyes)was given conventional therapy. The duration was 2wk.The ocular surface disease index scale(OSDI), ocular symptoms score \〖tear break-up time(BUT), Schirmer test(SⅠt), corneal fluorescein staining(CFS), limbi palpebralis scores, property of Meibomian secretion\〗, intraocular pressure, efficient rate were monitored.

RESULTS: Before treatment, the OSDI score, BUT, SⅠt, CFS, limbi palpebralis scores, property of Meibomian secretion and IOP were not significantly different between the two groups(P>0.05). OSDI score, CFS, limbi palpebralis scores, property of Meibomian secretion of the combined group was significantly lower than that of the control group(P<0.01). The post-treatment BUT and SⅠt of the combined group were significantly higher than those of the control group(P<0.01). No significant difference was found in post-treatment IOP between the two groups, either of the two groups higher than 21mmHg(P>0.05). The total effective rate of the combined group was 92.6%(100/108), while the total effective rate of control group was 78.6%(88/112, P<0.05).

CONCLUSION: Glass rod massage combined with conventional Meibomian gland dredging in the treatment of MGD can effectively ameliorate the ocular surface symptoms, Meibomian secretion function, and promote tear secretion.