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[摘要]
目的:探究双切口白内障超声乳化联合小梁切除术治疗对青光眼合并白内障患者视力、眼压和并发症的影响。
方法:回顾性分析2016-04/2017-10我院行双切口(观察组)和单切口(对照组)白内障超声乳化联合小梁切除术的青光眼合并白内障患者各68例68眼的临床资料。记录两组患者术前和术后1mo视力、角膜内皮细胞情况(密度、面积),以及术后1mo内并发症发生情况(前房积血、角膜内皮水肿、前房纤维素性渗出、滤过泡瘢痕化)差异,并比较两组患者术前和术后1、6mo眼压、散光程度差异。
结果:术后1mo时,两组患者视力均较术前升高,差异有统计学意义(P<0.05); 但组间比较,差异无统计学意义(P>0.05)。术后1mo时,两组患者角膜内皮细胞面积均较术前升高,差异有统计学意义(P<0.05); 角膜内皮细胞密度则较术前降低,差异有统计学意义(P<0.05),且对照组变化幅度均大于观察组,差异有统计学意义(P<0.05)。观察组术后并发症总发生率明显低于对照组,差异有统计学意义(P<0.05)。两组患者术后眼压均较术前降低,差异有统计学意义(P<0.05),但术后1mo与术后6mo比较,差异无统计学意义(P>0.05); 且两组间比较,差异无统计学意义(P>0.05)。两组患者术后散光程度均较术前升高,差异有统计学意义(P<0.05),且术后1mo高于术后6mo(P<0.05),而对照组均高于观察组,差异有统计学意义(P<0.05)。
结论:双切口白内障超声乳化联合小梁切除术治疗青光眼合并白内障患者效果显著,虽然双切口术式与单切口术式在改善视力和眼压方面效果相似,但双切口术式对术区损伤更小,能降低术后角膜内皮损伤,并减轻患者术后散光程度,还可减少术后并发症,于促进患者病情转归有积极意义。
[Key word]
[Abstract]
AIM: To explore the effects of double-incision phacoemulsification combined with trabeculectomy on visual acuity, intraocular pressure and complications in patients with glaucoma complicated with cataract.
METHODS: The clinical data of each 68 patients(68 eyes)with glaucoma and cataract who were given double-incision(observation group)and single-incision(control group)phacoemulsification combined with trabeculectomy from April 2016 to October 2017 were retrospectively analyzed. The visual acuity and corneal endothelial cell status(density, area)before operation and at 1mo after operation, and occurrence of complications(hyphema, corneal endothelial edema, anterior chamber fibrinous exudation, filtering bleb scarring)within 1mo after operation were recorded in the two groups. And the differences of intraocular pressure and astigmatism degree were compared between the two groups before operation and at 1 and 6mo after operation.
RESULTS:At 1mo after operation, the visual acuity in the two groups was better than that before operation(P<0.05). However, there was no significant difference between the two groups(P>0.05). At 1mo after operation, the area of corneal endothelial cell in the two groups was larger than that before operation(P<0.05)while the density of corneal endothelial cell was lower than that before operation(P<0.05), and the changes in control group were greater than those in observation group(P<0.05). The total incidence rate of postoperative complications in observation group was significantly lower than that in control group(P<0.05). The intraocular pressure in the two groups after operation was lower than that before operation(P<0.05), but there was no significant difference between at 1mo after operation and at 6mo after operation(P>0.05). And there was no statistically significant difference between the two groups(P>0.05). The postoperative astigmatism degree in the two groups was higher than that before operation(P<0.05), and the index at 1mo after operation was higher than that at 6mo after operation(P<0.05), and the index in control group was higher than that in observation group(P<0.05).
CONCLUSION:Double-incision phacoemulsification combined with trabeculectomy has significant effects on patients with glaucoma and cataract. Although double-incision surgery and single-incision surgery have similar effects in improving visual acuity and intraocular pressure, double-incision surgery has less damage to the operative area, and it can reduce the postoperative corneal endothelial injury and the postoperative astigmatism degree, and it can also reduce the postoperative complications, and has a positive significance in promoting the disease outcomes.
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