[关键词]
[摘要]
弱视是儿童视觉发育时期常见的眼科疾病之一，其发病机制较为复杂。本文对当前弱视发病机制的研究文献进行了总结，从视觉神经递质及其受体、细胞因子、相关基因和蛋白，以及调节激酶表达角度分析了视觉发育以及弱视发病的分子生物学机制。以期为视觉可塑性、弱视发病机制及治疗研究提供参考依据。
[Key word]
[Abstract]
Amblyopia is one of the common ophthalmic diseases in children's visual development, and its pathogenesis is rather complicated. This paper summarizes the current literatures on the pathogenesis of amblyopia, and analyzes the molecular biological mechanism of visual development and amblyopia pathogenesis from the visual neurotransmitters and their receptors, cell factors, related genes and proteins, as well as the expression of regulatory kinase. In order to provide a reference for the study of visual plasticity, amblyopia pathogenesis and treatment.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81860879,81660816,81260560); 甘肃中医药大学中青年科研基金项目(No.ZQ2015-1)
