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[摘要]
目的:探讨屈光不正性弱视治疗后期行视功能训练的临床疗效。
方法:前瞻性病例对照研究。选取2016-01/12在我院眼科门诊确诊为屈光不正性弱视患儿122例244眼作为研究对象。纳入标准:球镜≤±3.00D,散光度绝对值(以下简称散光度)≥2.00D,双眼球镜差值≤1.50D,双眼柱镜差值≤1.00D。所有患儿均已经过初步治疗,常规验光戴镜和弱视治疗后,弱视眼视力已经提高到0.6以上且双眼视力相差不超过2行。将患儿随机分为训练组(62例124眼)和对照组(60例120眼)。所有患儿均采用家庭+诊室训练相结合的方法。对照组训练内容为:弱视训练仪(光刷、红闪、光栅等)、电脑软件精细和刺激训练。训练组除完成对照组训练项目以外,还需要进行单眼调节功能、双眼调节功能训练及双眼集合、融像功能训练。随访6mo后,对两组患儿的视力疗效、近立体视、调节幅度、调节灵敏度和调节反应检查结果进行比较。
结果:随访末期,两组间整体的视力疗效比较,差异有统计学意义(P<0.05)。两组间近立体视功能、调节幅度、调节灵敏度和调节反应检查结果比较,差异有统计学意义(P<0.05)。
结论:屈光不正性弱视患儿在综合疗法治疗的基础上,后期行双眼视功能训练,对于提高弱视患儿的基本痊愈率、缩短疗程和建立健全立体视功能有一定作用。
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[Abstract]
AIM: To investigate the clinical efficacy of visual function training in the late stage of ametropic amblyopia treatment.
METHODS: One hundred and twenty two children patients and 244 eyes with ametropic amblyopia, which were ranged from January 2016 to December 2016, were enrolled in the prospective case control study. Patient inclusion criteria: spherical power≤ ±3.00D, absolute value of astigmatism(hereinafter referred to as the degree of astigmatism)≥2.00D, binocular spherical lens difference ≤1.50D, binocular cylinder difference ≤1.00D. All patients received preliminary treatment. After routine optometry and amblyopia treatment, visual acuity in amblyopic eyes improved to more than 0.6 and visual acuity difference between two eyes should be less than 2 lines in visual chart testing. Enrolled patients were randomly assigned into a training group(62 cases 124 eyes)and a control group(60 cases 120 eyes). All patients had routine glasses with a combination of both family and clinic training. Treatments in the control group included: amblyopia training instrument(light brush, red flash and grating etc.)and fine stimulation training through computer software. In addition to similar treatments in control group, patients in training group also received following treatments including monocular adjustment function training, binocular adjustment function training, binocular integration and fusion function training. After 6mo, visual acuity, near stereopsis, adjustment amplitude, adjustment sensitivity and adjustment response tests were compared and statistically analyzed in patients of both control and training groups.
RESULTS: Our data demonstrated that the overall visual acuity was significantly improved in training group(P<0.05). Additionally, results of near stereopsis function, adjustment amplitude, adjustment sensitivity and adjustment response examination, also displayed significant difference between the two groups(P<0.05).
CONCLUSION: Binocular visual function training has a certain effect in the improvement of successful cure rate, shortening treatment course and establishing a sound stereo vision function in the late stage of children patients receiving a comprehensive therapy.
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