目的：研究益精补阳还五汤辅治开角型青光眼患者对其眼压控制及预后影响效果。

方法：选取我院2015-07/2017-07收治的开角型青光眼患者93例186眼。按照随机数字表法将所有患者分为两组。观察组47例94眼，给予马来酸噻吗洛尔滴眼液结合益精补阳还五汤辅助治疗； 对照组46例92眼，仅使用马来酸噻吗洛尔滴眼液治疗。观察比较两组患者治疗后临床疗效，治疗前后视力、眼压、视网膜中央动脉血流测定值、平均缺损范围、视野平均光敏度以及图像诱发视觉电位情况。

结果：观察组治疗后总有效率明显高于对照组(85.1% vs 63.0%)(P<0.01)。治疗后，观察组眼压明显低于对照组(P<0.01)。观察组治疗后视网膜中央动脉血流RI测定值明显低于对照组(P<0.01)，PSA、EDV测定值明显高于对照组(P=0.011、<0.01)。观察组治疗后视野平均光敏度明显高于对照组(P=0.001)，平均缺损范围明显少于对照组(P=0.011)。

结论：使用益精补阳还五汤辅治开角型青光眼临床疗效显著，可有效控制患者眼压水平，扩大视野范围，促进血流循环，改善预后。

METHODS: Totally 93 patients(186 eyes)with open angle glaucoma admitted to our hospital from July 2015 to July 2017 were selected. All patients were divided into two groups according to the random number table method. In the observation group, 47 cases(94 eyes)were treated with timolol eye drop combined with Yijing Buyang Huanwu Decoction, and in the control group, 46 cases(92 eyes)were treated with timolol eye drop only. The clinical effect, visual acuity, intraocular pressure, central retinal artery blood flow, mean defect area, visual field average photosensitivity and image evoked visual potential were observed and compared before and after treatment.

RESULTS: The total effective rate of the observation group after treatment was significantly higher than that of the control group(85.1% vs 63.0%, P<0.01). After treatment, the intraocular pressure in the observation group was significantly lower than that in the control group(P<0.01). After treatment, RI values of central retinal artery blood flow in observation group were significantly lower than those in control group(P<0.01). PSA and EDV values were significantly higher than those in control group(P=0.011,<0.01). After treatment, the average photosensitivity of the observation group was significantly higher than that of the control group(P=0.001), and the average defect area was significantly less than that of the control group(P=0.011).

CONCLUSION: Yijing Buyang Huanwu Decoction is effective in the treatment of open angle glaucoma. It can effectively control the level of intraocular pressure, enlarge the visual field, promote blood circulation and improve the prognosis.