[关键词]
[摘要]
CRISPR/Cas系统原是在细菌的免疫系统内发现的用来抵抗外源遗传物质(如噬菌体病毒)的一种防御系统。由于其精确的靶向功能，CRISPR/Cas系统被开发成一种高效的基因编辑工具，被广泛地应用于生命科学研究的各个领域，并取得了革命性的进展。本文回顾性研究相关文献中关于CRISPR/Cas系统在人眼相关疾病中的应用，并进行总结。
[Key word]
[Abstract]
The CRISPR/Cas system was a defense system originally found in bacterial immune system against exogenous genetic material(such as phage virus). With the precision in its targeting function, CRISPR/Cas system has been developed into a highly efficient genome-editing tool that has been widely used in various fields of life science research and has achieved revolutionary progress. This paper reviews the relevant literature on the application of the CRISPR/Cas system in human eye diseases.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81301325)
