目的：研究糖尿病眼肌麻痹发生的相关危险因素。

方法：回顾性分析2008-06/2017-06就诊于青岛市市立医院眼科的糖尿病眼肌麻痹患者120例120眼的临床资料，根据颅神经受累部位分为动眼神经麻痹组(Ⅲ组，66例)、外展神经麻痹组(Ⅵ组，41例)、复合神经麻痹组(Ⅲ+Ⅵ组，13例)。收集所有患者的临床资料并进行统计分析，筛选糖尿病眼肌麻痹的相关危险因素。

结果：年龄、性别、糖尿病病程、糖化血红蛋白(HbA1c)水平、合并糖尿病视网膜病变(DR)和高血压情况与糖尿病眼肌麻痹的发生相关，其中年龄≥45岁，男性，糖尿病病程≥10a，合并DR，HbA1c>7%是糖尿病眼肌麻痹发生的独立危险因素。

结论：糖尿病眼肌麻痹的发生与糖尿病患者的年龄、性别、糖尿病病程、是否合并DR及HbA1c水平相关。

METHODS: The clinical data on 120 patients(120 eyes)with diabetic ophthalmoplegia treated in the Department of Ophthalmology in Qingdao Municipal Hospital from June 2008 to June 2017 were retrospectively analyzed. In terms of cranial nerve involvement, patients were divided into three groups: those with oculomotor nerve paralysis(group Ⅲ, 66), abducent nerve paralysis(group Ⅵ, 41), and compound nerve paralysis(groups Ⅲ+Ⅵ, 13). The clinical data of patients were collected and statistically analyzed to screen the related risk factors of diabetic ophthalmoplegia.

RESULTS: Age, gender, diabetes duration, HbA1c level, diabetic retinopathy and hypertension were related to diabetic ophthalmoplegia. Age≥45 years, male gender, diabetes duration≥10a, retinopathy, and HbA1c>7% were independent risk factors for diabetic ophthalmoplegia.

CONCLUSION: The occurrence of diabetic ophthalmoplegia is related to the age, gender, diabetes duration, diabetic retinopathy and HbA1c level.