目的：探讨不同程度近视患者黄斑参数改变的相关因素。

方法：选取2016-01/2017-12在我院眼科就诊的自愿参加研究的近视患者313例626眼，使用OCT对其黄斑中心区厚度、黄斑内外环的颞侧、上方、鼻侧及下方各区域的厚度进行测量，分析黄斑参数与年龄、性别、眼别、眼轴长度(AL)以及等效球镜(SE)的相关性。

结果：三组不同程度近视患者的黄斑中心区视网膜厚度最薄，黄斑区内环上方与内环鼻侧视网膜厚度最厚，三组间的内环鼻侧、内环上方、内环颞侧、内环下方、外环鼻侧、外环上方、外环颞侧、外环下方的视网膜厚度均有差异(P<0.05)。黄斑中心及内外环内部不同区域的视网膜厚度与年龄、眼别均无相关性(P>0.05)，与性别相关(P<0.05)； 除黄斑中心外，内外环内部不同区域的视网膜厚度与AL呈负相关，与SE呈正相关(P<0.05)。

结论：近视患者的黄斑参数与AL、SE有一定的相关性。

METHODS: Totally 313 myopia patients who volunteered to participate in the study were selected and divided into mild, moderate and severe myopia groups. Optical coherence tomography(OCT)was used to measure the central area of the macula thickness, the temporal, upper, nasal and lower areas of the inner and outer ring. And the correlation between the macular parameters and age, gender, different of eyes, axial length and spherical equivalent were analyzed.

RESULTS: The central fovea of macula was the thinnest. The superior and the nasal of inner ring were the thinner among all parts of macular and there were significant differences in macular thickness among three groups(P<0.05). Correlation analysis showed that there was no correlation between the macular thickness and age, different of eyes(P>0.05). Macular thickness in different areas were correlated with gender, and the thickness in women was thinner than men(P<0.05). The macula thickness in all areas of the inner and outer ring was negatively correlated with axial length except the center(P<0.05). The macula thickness in all areas of the inner and outer ring positively correlated with spherical equivalent except the center(P<0.05).

CONCLUSION: The macular parameters of myopia were closely linked to the spherical equivalent and axial length.