目的：探讨不同程度的真菌性角膜溃疡综合治疗的效果及临床转归。

方法：收集我院2017-11/2018-02确诊为真菌性角膜溃疡患者85例85眼，根据病情的严重程度，采取11项综合措施治疗，围手术期药物治疗，应用相应的手术治疗，所有患者随访6～8mo，观察角膜溃疡愈合情况及最终疾病转归。

结果：真菌性角膜溃疡平均住院时间12d，85眼中有79眼(93%)治愈， 好转5眼(6%)，无效1眼(1%)。

结论：真菌性角膜溃疡采用全身及局部药物治疗，联合手术治疗，据病变深度及范围分别行角膜清创术、碘酊烧灼术、羊膜移植术、结膜瓣遮盖术、治疗性角膜移植术等综合方法治疗，才能收到理想的治疗效果，保留及恢复视力。

METHODS: Totally 85 cases(85 eyes)of fungal corneal ulcer diagnosed in our hospital from November 2017 to February 2018 were determined according to the severity of the disease. Took 11 comprehensive measures to treat, they were treated with corresponding drugs and combined operation respectively, all patients were followed up for 6-8mo to observe corneal ulcer healing and final disease outcomes.

RESULTS: The average length of hospital stay for fungal corneal ulcer was 12d, and 79 eyes were cured in 85 eyes. The cure rate was 93%, 5 eyes improved(6%), and 1 eye was invalid(1%).

CONCLUSION: Systemic and local drug therapy for fungal corneal ulcer, the operation was performed by corneal debridement, iodine cautery, conjunctival flap covering, amniotic membrane transplantation and keratoplasty, which will receive ideal therapeutic effects and restore vision.