目的：探讨YAG激光联合RS引流管治疗泪道阻塞的疗效及独立影响因素。

方法：回顾性分析2015-01/2018-01在我院行激光联合引流管置入治疗的250例泪道阻塞患者病例资料，总结术后疗效并采用Logistic回归分析影响疗效的独立因素。

结果：患者术后临床治疗总有效率为87.9%； 病程(OR=8.654，95% CI：3.740～20.023)、泪道冲洗频率(OR=3.480，95% CI：2.128～5.691)、泪道阻塞长度(OR=0.518，95% CI：0.238～1.131)、拔管时间(OR=0.386，95% CI：0.237～0.628)以及首次手术(OR=14.717，95% CI：10.798～20.059)是影响患者术后疗效独立影响因素。

结论：YAG激光联合RS引流管置入治疗泪道阻塞疗效显著，早期治疗、避免多次手术、术后适度冲洗泪道、控制拔管时间，均有利于提高疗效。

METHODS: Retrospective analysis of the cases of 250 patients with lacrimal duct obstruction treated by laser combined drainage tube in our hospital from 2015-01/2018-01, summarized the efficacy and analyzed the independent factors of efficacy.

RESULTS: The total effective rate of clinical treatment was 87.9%; course of disease(OR=8.654, 95% CI: 3.740-20.023), frequency of lacrimal passage(OR=3.480, 95% CI: 2.128-5.691), length of lacrimal duct obstruction(OR=0.518, 95% CI: 0.238-1.131), extubation time(OR=0.386, 95% CI: 0.237-0.628)and initial surgery(OR=14.717, 95% CI: 10.798-20.059)were the independent factor influencing the efficacy.

CONCLUSION: YAG laser combined with RS disposable drainage tube is effective in the treatment of lacrimal duct obstruction. Early treatment, avoiding multiple operations, proper irrigation of lacrimal passage after operation, and controlling extubation time, which are beneficial to improve the curative effect and improve the prognosis of patients.